| Plattsmouth Main Street Historic District | |
| Location: | Main St. bounded by Avenue A, S. and N. 3rd St., 1st Ave. and S. and N. 7th St., Plattsmouth, Nebraska |
| Coordinates: | 41.0114°N -95.8844°W |
| Built: | 1869 |
| Architecture: | Classical Revival, Italianate, Romanesque |
| Added: | September 26, 1985 |
| Area: | 11acres |
| Refnum: | 85002585 |
The Plattsmouth Main Street Historic District, in Plattsmouth, Nebraska, is a historic district which was listed on the National Register of Historic Places in 1985. The listing included 45 contributing buildings on 11acres.
It is in the area of Main St. bounded by Avenue A, S. and N. 3rd St., 1st Ave. and S. and N. 7th St. in Plattsmouth.
It includes: