Plasmodium chiricahuae is a parasite of the genus Plasmodium subgenus Paraplasmodium.
Like all Plasmodium species P. chiricahuae has both vertebrate and insect hosts. The vertebrate hosts for this parasite are reptiles.
The schizonts rarely exceed the size of the nucleus of the cell and produce 4-10 merozoites.
The gametocytes are large (3-6 times the size of the nucleus of an uninfected cell) and almost fill the erythrocyte.
This species is found in the south-western United States and probably also in northern Mexico.
This species infects spiny lizards of the genus Sceloporus.