Placental villous immaturity explained

Placental villous immaturity
Field:	Gynecology, pathology
Synonyms:	Villous immaturity, villous dysmaturity

Placental villous immaturity is chorionic villous development that is inappropriate for the gestational age.

It is associated with diabetes mellitus^[1] and fetal death near term, i.e. intrauterine demise close to the normal gestational period.^[2]

Pathology

Immature chorionic villi are larger and have more central blood vessels; thus, the diffusion distance for gas and nutrient exchange is larger and, therefore, placental function is impaired.

See also

• Placenta
• Placental pathology

Notes and References

1. Arizawa . M. . Nakayama . M. . Kidoguchi . K. . [Correlation of placental villous immaturity and dysmaturity with clinical control of maternal diabetes]. . Nihon Sanka Fujinka Gakkai Zasshi . 43 . 6 . 595–602 . Jun 1991 . 1856519 .
2. Stallmach . T. . Hebisch . G. . Placental pathology: its impact on explaining prenatal and perinatal death. . Virchows Arch . 445 . 1 . 9–16 . Jul 2004 . 10.1007/s00428-004-1032-2 . 15138817 . 12463921 .