| Pithole Creek | |
| Name Other: | Tributary to Allegheny River |
| Map Size: | 300 |
| Pushpin Map: | USA Pennsylvania |
| Pushpin Map Size: | 300 |
| Pushpin Map Caption: | Location of the mouth of Pithole Creek in Pennsylvania |
| Subdivision Type1: | Country |
| Subdivision Name1: | United States |
| Subdivision Type2: | State |
| Subdivision Name2: | Pennsylvania |
| Subdivision Type3: | Counties |
| Subdivision Name3: | Forest, Venango |
| Length: | 17.1miles |
| Discharge1 Location: | Allegheny River |
| Discharge1 Avg: | 74.06cuft/s at mouth with Allegheny River[1] |
| Source1 Location: | Stewart Run, Forest County, Pennsylvania |
| Source1 Coordinates: | 41.6222°N -79.4939°W |
| Source1 Elevation: | 1720feet[2] |
| Mouth: | Allegheny River |
| Mouth Location: | Oleopolis, Venango County, Pennsylvania |
| Mouth Coordinates: | 41.4564°N -79.6097°W[3] |
| Mouth Elevation: | 1010feet |
| Basin Size: | 41.8sqmi |
| Tributaries Left: | Simmons Run |
| Tributaries Right: | Woodcock Run Schoolhouse Run W Pithole Creek Allender Run |
Pithole Creek is a 17.1miles tributary of the Allegheny River in Northwest Pennsylvania in the United States.[4] It has a drainage area of .
Pithole Creek joins the Allegheny River approximately upstream of Oleopolis.[4]