Pipeline Pilot Explained

Pipeline Pilot
Developer:Accelrys
Latest Release Version:18.1
Programming Language:C++
Operating System:Windows and Linux
Genre:Visual and dataflow programming language
License:Proprietary

Pipeline Pilot is a desktop software program sold by Dassault Systèmes for processing and analyzing data. It was originally used for its basic ETL (extract, transform, and load) and analytics capabilities, which have broadened over time.

The program has the ability to design data workflows using a graphical user interface. It is a visual and dataflow programming software and has been used in cheminformatics, QSAR,[1] [2] [3] Next Generation Sequencing,[4] image analysis,[5] [6] and text analytics.

History

Pipeline Pilot was created by SciTegic. BIOVIA subsequently acquired SciTegic and Pipeline Pilot in 2004. BIOVIA was itself purchased by Dassault Systèmes in 2014.

The product expanded from an initial focus on chemistry to include general extract, transform, and load (ETL), analytical, and data processing collection capabilities.

Overview

Pipeline Pilot is part of a class of software products that provide user interfaces for manipulating and analyzing data. Like other graphical ETL products, it enables users to pull from different data sources, such as CSV files, text files, and databases.

The graphical user interface, called the Pipeline Pilot Professional Client, allows users to drag and drop discrete data processing units called "components". Components can load, filter, join, or manipulate data. Components can also build regression models, train neural networks, or process datasets into PDF reports. Pipeline Pilot implements a component paradigm. Components are represented as nodes in a workflow. In a mathematical sense, components are modeled as nodes in a directed graph: "pipes" (graph edges) connect components and move data along from node to node, where operations are performed on the data.

Users can choose from components that come pre-installed or create their own components in workflows called "protocols". Protocols are sets of linked components. Protocols can be saved, reused, and shared. Users can mix and match components that are provided with the software from BIOVIA with their own custom components. Connections between two components are called "pipes", and are visualized in the software as two components connected by a pipe. Data flows from left to right along the pipes. Pipeline Pilot can visually condense a series of data manipulations that involve many components.

Component collections

Pipeline Pilot features a number of add-ons called "collections". Collections are groups of specialized functions like processing genetic information or analyzing polymers offered to end users for an additional licensing fee. Currently, there are a number of these collections.[7]

Group Domain Component collection
Science specificChemistryChemistry
ADMET
Cheminformatics
BiologyGene Expression
Sequence Analysis
Mass Spectrometry for Proteomics
Next Generation Sequencing
Materials Modeling & SimulationMaterials Studio
Polymer Properties (Synthia)
GenericReporting & VisualizationReporting
Database & Application IntegrationIntegration
ImagingImaging
Analysis & StatisticsData Modeling
Advanced Data Modeling
R Statistics
Document Search & AnalysisChemical Text Mining
Text Analytics
LaboratoryPlate Data Analytics
Analytical Instrumentation

Custom scripts

Pipeline Pilot is often used when one or more large (1TB+) and/or complex datasets are processed. Early in its development, Pipeline Pilot created a scripting language called "PilotScript" that enabled end users to write basic programming scripts that could be incorporated into a Pipeline Pilot protocol. Later releases extended support for a variety of programming languages, including Python, .NET, Matlab, Perl, SQL, Java, VBScript and R.[8] The product supports a number of APIs for different programming languages that can be executed without the program's graphical user interface.

The syntax for PilotScript is based on PLSQL. It can be used in components such as the Custom Manipulator (PilotScript) or the Custom Filter (PilotScript). As an example, the following script can be used to add a property named "Hello" to each record passing through a custom scripting component in a Pipeline Pilot protocol. The value of the property is the string "Hello World!".

Hello := "Hello World!";

Notes and References

  1. Hassan. Moises. Brown. Robert D.. Varma-O'Brien. Shikha. Rogers. David. Cheminformatics Analysis and Learning in a Data Pipelining Environment. ChemInform. 38. 12. 2007. 0931-7597. 10.1002/chin.200712278.
  2. Hu. Ye. Lounkine. Eugen. Bajorath. Jürgen. Improving the Search Performance of Extended Connectivity Fingerprints through Activity-Oriented Feature Filtering and Application of a Bit-Density-Dependent Similarity Function. ChemMedChem. 4. 4. 2009. 540–548. 1860-7179. 10.1002/cmdc.200800408. 19263458. 35868099.
  3. Warr. Wendy A.. Scientific workflow systems: Pipeline Pilot and KNIME. Journal of Computer-Aided Molecular Design. 26. 7. 2012. 801–804. 0920-654X. 10.1007/s10822-012-9577-7. 22644661. 3414708. 2012JCAMD..26..801W.
  4. Web site: Accelrys Enters Next Generation Sequencing Market with NGS Collection for Pipeline Pilot. Business Wire. 15 February 2013. 2011-02-23.
  5. Rabal. Obdulia. Link. Wolfgang. G. Serelde. Beatriz. Bischoff. James R.. Oyarzabal. Julen. An integrated one-step system to extract, analyze and annotate all relevant information from image-based cell screening of chemical libraries. Molecular BioSystems. 6. 4. 2010. 711–20. 1742-206X. 10.1039/b919830j. 20237649.
  6. Paveley. Ross A.. Mansour. Nuha R.. Hallyburton. Irene. Bleicher. Leo S.. Benn. Alex E.. Mikic. Ivana. Guidi. Alessandra. Gilbert. Ian H.. Hopkins. Andrew L.. Bickle. Quentin D.. Whole Organism High-Content Screening by Label-Free, Image-Based Bayesian Classification for Parasitic Diseases. PLOS Neglected Tropical Diseases. 6. 7. 2012. e1762. 1935-2735. 10.1371/journal.pntd.0001762. 22860151. 3409125. free.
  7. Web site: Pipeline Pilot Component Collections. Accelrys. 26 January 2013. dead. https://web.archive.org/web/20130115123007/http://accelrys.com/products/pipeline-pilot/component-collections.html. January 15, 2013.
  8. Web site: Pipeline Pilot Integration Component Collection Datasheet. Accelrys. 8 February 2013.