Pinoxepin Explained

Pinoxepin (; developmental code name P-5227; pinoxepin hydrochloride) is an antipsychotic of the tricyclic group with a dibenzoxepin ring system which was developed in the 1960s but was never marketed.^{[1] [2] [3] [4] [5]} It was found in clinical trials to have effectiveness in the treatment of schizophrenia similar to that of chlorpromazine and thioridazine. The drug has marked sedative effects but causes relatively mild extrapyramidal symptoms.

Notes and References

1. Book: Elks J . The Dictionary of Drugs: Chemical Data: Chemical Data, Structures and Bibliographies. 14 November 2014. Springer. 978-1-4757-2085-3. 984–.
2. Book: Annual Reports in Medicinal Chemistry. 1 January 1967. Academic Press. 978-0-08-058346-4. 2–.
3. Book: Gordon M . Psychopharmacological Agents. 2 December 2012. Elsevier Science. 978-0-323-15128-3. 102–.
4. Book: Iversen L . Handbook of Psychopharmacology: Volume 10: Neoroleptics and Schizophrenia. 6 December 2012. Springer Science & Business Media. 978-1-4613-4042-3. 200–.
5. Book: Lajtha A . Alterations of Metabolites in the Nervous System. 11 November 2013. Springer Science & Business Media. 978-1-4757-6740-7. 335–.