Pinchas Cohen Explained

Pinchas Cohen is the dean of the USC Leonard Davis School of Gerontology, holds the William and Sylvia Kugel Dean's Chair in Gerontology and serves as the executive director of the Ethel Percy Andrus Gerontology Center.

Cohen graduated in 1986 with highest honors from the medical school at Technion in Israel and trained at Stanford University between 1986 and 1992. He held his first faculty position at the University of Pennsylvania from 1992 to 1999. Until summer 2012, he was a professor and vice chair for research at the Mattel Children's Hospital UCLA at the Ronald Reagan UCLA Medical Center, as well as the co-director of the UCSD/UCLA Diabetes Research Center.[1] [2] He served on the advisory board for the Milken Institute Center for the Future of Aging.[3]

Research

He received numerous awards for his research, including a National Institute of Aging "EUREKA"-Award and the NIH-Director-Transformative R01-Grant. He also recently received the Glenn Award for Research in Biological Mechanisms of Aging. Cohen's research focuses on aging, neurodegeneration, cancer and diabetes with an emphasis on the emerging science of mitochondrial-derived peptides, which he discovered.[4] [5] He has also discussed the possibilities of applying personalized medicine to aging science, coining the term "personalized aging."[6] [7]

His laboratory was one of three teams that independently discovered humanin (Cohen and his team had been screening for proteins that interact with IGFBP3[8]). Other mitochondrial peptides discovered by the Cohen laboratory include SHLP 1, 2, 3, 4, 5, and 6[9] [10] and MOTS-C.[11] [12]

He holds several patents for novel peptides and is the co-founder of CohBar,[13] a biotechnology company developing peptides found in mitochondria for diabetes treatment.[14] Cohen has published more than 250 papers in top scientific journals.

An expert in the field, Cohen was president of the Growth Hormone Society and served on the Endocrine Society Steering Committee.[15] [16] [17] He has sat on multiple NIH study sections and on several editorial boards.[18]

Notes and References

  1. Web site: Pinchas Cohen Named Dean of USC Davis School of Gerontology. USC. 23 July 2012.
  2. Web site: Curriculum Vitae. USC Leonard Davis School of Gerontology . 3 January 2017.
  3. "Milken Institute Center for the Future of Aging Assembles Top Experts on Aging." December 1, 2015. http://www.milkeninstitute.org/newsroom/press-releases/view/288.
  4. Web site: Cohen Lab.
  5. Web site: Pinchas Cohen. USC Leonard Davis School of Gerontology. 3 January 2017.
  6. Web site: Personalized Aging. 23 May 2016. Next Avenue.
  7. Web site: USC's Cohen on Personalized Aging, U.S. Health Care. Bloomberg.
  8. Ikonen. M. Liu, B . Hashimoto, Y . Ma, L . Lee, KW . Niikura, T . Nishimoto, I . Cohen, P . Interaction between the Alzheimer's survival peptide humanin and insulin-like growth factor-binding protein 3 regulates cell survival and apoptosis. Proceedings of the National Academy of Sciences of the United States of America. Oct 28, 2003. 100. 22. 13042–7. 14561895. 10.1073/pnas.2135111100. 240741. 2003PNAS..10013042I. free.
  9. Cobb, L. J., Lee, C., Xiao, J., Yen, K., Wong, R. G., Nakamura, H. K., … Cohen, P. (2016). Naturally occurring mitochondrial-derived peptides are age-dependent regulators of apoptosis, insulin sensitivity, and inflammatory markers. Aging, 8(4), 796–808. http://doi.org/10.18632/aging.100943.
  10. Web site: Small peptides show neuroprotective properties. Alzheimer's News Today. 3 January 2017.
  11. Lee et al., 2015, Cell Metabolism 21, 443–454. March 3, 2015 ª2015 Elsevier Inc. https://dx.doi.org/10.1016/j.cmet.2015.02.009.
  12. Web site: Newly discovered hormone helps mice lose weight. Popular Science. 3 January 2017.
  13. Web site: Pinchas Cohen, M.D. – Founder and Director – CohBar Inc. . cohbar.com . dead . https://web.archive.org/web/20170104163213/http://cohbar.com/management/pinchas-cohen-m-d-founder-and-director/ . 2017-01-04.
  14. Web site: Company Overview of CohBar, Inc.. Bloomerg Businessweek. 23 July 2012.
  15. News: Dunkel. Tom. Vigor Quest. The New York Times. 23 July 2012. 2010-01-15.
  16. Web site: USC Davis School of Gerontology Faculty Profile: Pinchas Cohen, M.D.. USC. 23 July 2012.
  17. Web site: Recognizing and Overcoming Adherence Barriers in the Pediatric Setting: An Expert Interview With Pinchas Cohen, MD. Medscape. 23 July 2012.
  18. Web site: Curriculum Vitae. USC Leonard Davis School of Gerontology . 3 January 2017.

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