| Type: | suburb |
| Piesse Brook | |
| City: | Perth, Western Australia |
| State: | wa |
| Lga: | City of Kalamunda |
| Map Type: | nomap |
| Local Map: | yes |
| Zoom: | 12 |
| Coordinates: | -31.971°N 116.08°W |
| Postcode: | 6076 |
| Stategov: | Darling Range |
| Fedgov: | Hasluck |
| Near-Nw: | Gooseberry Hill |
| Near-N: | Darlington |
| Near-Ne: | Paulls Valley |
| Near-W: | Gooseberry Hill |
| Near-E: | Paulls Valley |
| Near-Sw: | Kalamunda |
| Near-S: | Bickley |
| Near-Se: | Hacketts Gully |
Piesse Brook is a suburb of Perth, Western Australia in the City of Kalamunda. It was officially named in 1972, although the name had been in use since 1890 for a watercourse in the area which honoured William Roper Piesse, a prominent citizen with a large family who were based in Guildford.