| San Canzian d'Isonzo | |
| Official Name: | Comune di San Canzian d'Isonzo |
| Coordinates: | 45.8°N 41°W |
| Region: | Friuli-Venezia Giulia |
| Province: | Gorizia (GO) |
| Frazioni: | Begliano, Isola Morosini, Pieris, Terranova |
| Mayor Party: | PD |
| Mayor: | Silvia Caruso |
| Area Total Km2: | 33.6 |
| Population Total: | 6394 |
| Population As Of: | 2008 |
| Elevation M: | 8 |
| Saint: | Cantius, Cantianus and Cantianilla |
San Canzian d'Isonzo (Bisiacco: Sacanziàn; ;) is a Italian: [[comune]] (municipality) in the Regional decentralization entity of Gorizia in Friuli-Venezia Giulia, northeast Italy.
The small town is situated about 30km (20miles) from Gorizia, the capital of the province, and west of the important port of Trieste. Its name refers to the martyrs Cantius, Cantianus, and Cantianilla, who are said to have been beheaded here in 304 AD.
It is also the birthplace of Italian footballer and former AC Milan manager Fabio Capello.