| Picerno | |
| Official Name: | Comune di Picerno |
| Coordinates: | 40.6333°N 53°W |
| Region: | Basilicata |
| Province: | Potenza (PZ) |
| Mayor: | Giovanni Lettieri |
| Area Total Km2: | 78 |
| Population Total: | 6109 |
| Population As Of: | 31 December 2009 |
| Population Demonym: | Picernesi |
| Elevation M: | 721 |
| Saint: | St. Nicholas |
| Day: | 9 May and 6 December |
| Postal Code: | 85055 |
| Area Code: | 0971 |
Picerno is a town and comune in the province of Potenza, in the Southern Italian region of Basilicata. It is bounded by the comuni of Balvano, Baragiano, Potenza, Ruoti, Savoia di Lucania, Tito, and Vietri di Potenza.