Physalaemus moreirae is a species of frog in the family Leptodactylidae. It is endemic to the Serra do Mar in the São Paulo state, Brazil.
Males measure 25mm27mm and females 25mm28mm in snout–vent length.
Its natural habitats are primary forests where it occurs in leaf-litter or on stones near water, often in association with small temporary pools (even those formed in boot prints). However, breeding takes place in temporary streams; the eggs are laid in foam nests in wide pools in the streams. Habitat loss is a probable threat. Also chytridiomycosis could be a threat.