2-(1-Hexyloxyethyl)-2-devinyl pyropheophorbide-a explained

2-(1-Hexyloxyethyl)-2-devinyl pyropheophorbide-a (HPPH) is a photosensitiser chemical that is used in photodynamic therapy.[1]

It is being developed under the brand name Photochlor.

Clinical trials

A phase I/II clinical trial started in 1997 for esophageal cancer.[2]

A phase II trial for non-small cell lung cancer is due to run from 2007 to 2011.[3]

External links

Notes and References

  1. 11891727 . 2001 . Lobel . J . MacDonald . IJ . Ciesielski . MJ . Barone . T . Potter . WR . Pollina . J . Plunkett . RJ . Fenstermaker . RA . Dougherty . TJ . 2-1-hexyloxyethyl-2-devinyl pyropheophorbide-a (HPPH) in a nude rat glioma model: implications for photodynamic therapy . 29 . 5 . 397–405 . Lasers in Surgery and Medicine . 10.1002/lsm.10001 . 22578518 .
  2. http://clinicaltrials.gov/ct2/show/NCT00060268 Photodynamic Therapy Using HPPH in Treating Patients With Obstructive Esophageal Tumors
  3. http://clinicaltrials.gov/ct2/show/NCT00528775 Photodynamic Therapy Using HPPH in Treating Patients With Advanced Non-Small Cell Lung Cancer That Blocks the Air Passages

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