Pheophorbidase Explained

Pheophorbidase
Ec Number:	3.1.1.82

Pheophorbidase (EC 3.1.1.82, phedase, PPD) is an enzyme with systematic name pheophorbide-a hydrolase.^{[1] [2] [3]} It catalyses the following reaction:

pheophorbide a + H₂O

\rightleftharpoons pyropheophorbide a + methanol + CO₂ (overall reaction)

(1a) pheophorbide a + H₂O

\rightleftharpoons C-13²-carboxypyropheophorbide a + methanol

(1b) C-13²-carboxypyropheophorbide a

\rightleftharpoons pyropheophorbide a + CO₂ (spontaneous)

This enzyme participates in the chlorophyll degradation in higher plants and algae.

Notes and References

1. Suzuki Y, Doi M, Shioi Y . Two enzymatic reaction pathways in the formation of pyropheophorbide a . Photosynthesis Research . 74 . 2 . 225–33 . 2002 . 16228561 . 10.1023/A:1020919929608 .
2. Suzuki Y, Amano T, Shioi Y . Characterization and cloning of the chlorophyll-degrading enzyme pheophorbidase from cotyledons of radish . Plant Physiology . 140 . 2 . 716–25 . February 2006 . 16384908 . 1361337 . 10.1104/pp.105.071290 .
3. Hörtensteiner S . Chlorophyll degradation during senescence . Annual Review of Plant Biology . 57 . 55–77 . 2006 . 16669755 . 10.1146/annurev.arplant.57.032905.105212 .