| Persimmon Run | |
| Name Other: | Tributary to West Branch Christina River |
| Map Size: | 180 |
| Map Alt: | Map of Persimmon Run mouth |
| Pushpin Map: | Delaware#USA |
| Pushpin Map Size: | 180 |
| Pushpin Map Alt: | Location of Persimmon Run mouth |
| Subdivision Type1: | Country |
| Subdivision Name1: | United States |
| Subdivision Type2: | State |
| Subdivision Name2: | Delaware Maryland |
| Subdivision Type3: | County |
| Subdivision Name3: | New Castle (DE) Cecil (MD) |
| Length: | 1.69miles[1] |
| Discharge1 Location: | West Branch Christina River |
| Discharge1 Avg: | 2.39cuft/s at mouth with West Branch Christina River[2] |
| Source1: | Big Elk Creek divide |
| Source1 Location: | Cecil County Airpark, Cecil County, Maryland |
| Source1 Coordinates: | 39.6469°N -75.8°W[3] |
| Source1 Elevation: | 123feet[4] |
| Mouth: | West Branch Christina River |
| Mouth Location: | Anvil Park, Delaware |
| Mouth Coordinates: | 39.6544°N -75.7758°W |
| Mouth Elevation: | 92feet |
| Progression: | southeast then northeast |
| River System: | Christina River |
| Tributaries Left: | unnamed tributaries |
| Tributaries Right: | unnamed tributaries |
| Bridges: | Elkton Road, Iron Hill Road, Otts Chapel Road |
Persimmon Run is a 1.69adj=midNaNadj=mid 1st order tributary to the West Branch Christina River in New Castle County, Delaware in the United States.
Persimmon Run rises on the Big Elk Creek divide in Cecil County, Maryland and flows southeast then northeast into New Castle County, Delaware meet the West Branch Christina River at Anvil Park, Delaware.
Persimmon Run drains of area, receives about 46.2 in/year of precipitation, has a topographic wetness index of 503.39 and is about 21.7% forested.[2]