Perlia's nucleus, also known as nucleus of Perlia, located in the mesencephalon and between the right and left oculomotor nuclei, is implicated in parasympathetic oculomotor functions, possibly including input to the iris and ciliary.[1] Perlia's nucleus is believed to be a characteristic found exclusively in animals capable of binocular vision. Moreover, it might be an exclusive characteristic of humans, as indicated by a systematic study of monkey brains, where only 9% exhibited a clear midline group, potentially corresponding to the NP.[2]
In 1891, Perlia's nucleus was identified as a central mediator for the convergent movement of the eyes based on clinical findings in ophthalmospegias.[3]