| Official Name: | Perkins, Missouri |
| Settlement Type: | Census-Designated Place |
| Subdivision Type: | Country |
| Subdivision Name: | United States |
| Subdivision Type1: | State |
| Subdivision Name1: | Missouri |
| Subdivision Type2: | County |
| Subdivision Name2: | Scott |
| Unit Pref: | Imperial |
| Area Footnotes: | [1] |
| Area Total Km2: | 0.43 |
| Area Land Km2: | 0.43 |
| Area Water Km2: | 0.00 |
| Area Total Sq Mi: | 0.17 |
| Area Land Sq Mi: | 0.17 |
| Area Water Sq Mi: | 0.00 |
| Population As Of: | 2020 |
| Population Total: | 123 |
| Population Density Km2: | 287.73 |
| Population Density Sq Mi: | 745.45 |
| Elevation Ft: | 338 |
| Postal Code Type: | ZIP code |
| Postal Code: | 63771[2] |
| Area Code: | 573 |
| Blank Name: | FIPS code |
| Blank Info: | 29-57044 |
| Blank1 Name: | GNIS feature ID |
| Blank1 Info: | 724226 |
Perkins is an unincorporated community and census-designated place in western Scott County, Missouri, United States. It is located sixteen miles northwest of Sikeston.
A post office called Perkins has been in operation since 1890.[3] The community has the name of Amos Perkins, a businessperson in the local lumber industry.[4]
Perkins is found in the St. Louis Southwestern Railway Northern Division Employee Time Table No. 10 dated August 18, 1935. Perkins was station I-24 at milepost 23.76. It had a 20 car siding. In 1935 terms that was 900 feet long, as the then standard car was 45 feet in length. There was a mail crane at Perkins. It was a flagstop for passenger trains #5 and #6. Nearby Randles had a day/night telegraph and long lap sidings to meet trains.