| Periya Kalayamputhur | |
| Native Name: | பெரிய கலயம்புத்தூர் |
| Native Name Lang: | ta |
| Settlement Type: | Village |
| Pushpin Map: | India Tamil Nadu |
| Pushpin Label Position: | left |
| Pushpin Map Caption: | Location in Tamil Nadu, India |
| Subdivision Type: | Country |
| Subdivision Name: |  India |
| Subdivision Type1: | State |
| Subdivision Name1: | Tamil Nadu |
| Subdivision Type2: | District |
| Subdivision Name2: | Dindigul |
| Unit Pref: | Metric |
| Population Total: | 11746 |
| Population As Of: | 2011 |
| Population Density Km2: | auto |
| Demographics Type1: | Languages |
| Demographics1 Title1: | Official |
| Demographics1 Info1: | Tamil |
| Timezone1: | IST |
| Utc Offset1: | +5:30 |
| Postal Code Type: | PIN |
| Postal Code: | 624615/635158 |
| Area Code Type: | Telephone code |
Periya Kalayamputhur is a panchayat village located in the Palani Block in Dindigul district of Tamil Nadu, India. It is situated 5 km from sub-district headquarter Palani and 60 km away from the district headquarter of Dindigul. The village covers an area of 1412.67 hectares and has a total population of 11,746, including 5,730 males and 6,016 females, according to 2011 census. There are about 3,171 houses in the village.