Perdur Radhakantha Adiga Explained
Perdur Radhakantha Adiga (5 May 1935 – 13 September 2006) was an Indian endocrine biochemist, reproductive biologist, INSA Senior Scientist[1] and an Astra chair professor of the Indian Institute of Science.[2] He was known for his researches on vitamin-carrier proteins and Lathyrus sativus[3] and was an elected fellow of the Indian Academy of Sciences[4] and the Indian National Science Academy.[5] The Council of Scientific and Industrial Research, the apex agency of the Government of India for scientific research, awarded him the Shanti Swarup Bhatnagar Prize for Science and Technology, one of the highest Indian science awards for his contributions to Medical Sciences in 1980.[6]
Biography
P. R. Adiga, born on 5 May 1935 at Barkur, a small hamlet in Udupi district of the south Indian state of Karnataka as one among the ten children of his parents, did his early schooling at local schools and earned a master's degree in biochemistry from the University of Kerala in the neighboring state.[7] Subsequently, he joined the Indian Institute of Science as a research associate and pursued his doctoral studies under the guidance of P. S. Sarma, who headed the department of biochemistry, to secure the degree in 1963. He spent his entire career at IISc, holding various positions as that of an assistant professor, associate professor and professor. He also chaired the erstwhile Centre for Reproductive Biology and Molecular Endocrinology at the institute. Post retirement, he continued his association with IISc as an INSA Senior scientist.
Adiga's early researches were focused on the growth and intermediary metabolism of fungi and insects and how they were impacted by the trace elements and metal toxicity. His work on Lathyrus sativus, commonly known as grass pea, revealed that N-oxalyl-diaminopropionic acid, a neurotoxin present in the plant caused the neurological disorder of neurolathyrism in humans. He was also credited with the discovery of Homoarginine, an amino acid derivative, found in Lathyrus sativus. Later, he worked on vitamin-carrying proteins which demonstrated how the proteins carried vitamins such as thiamin and riboflavin to the foetus and his experiments on rodents showed antibodies generated during pregnancy might cause its termination.[8] He documented his researches by way of several articles in peer-reviewed journals[9] and the online article repository of the Indian Academy of Sciences has listed 192 of them.[10] He edited the book, Perspectives in Primate Reproductive Biology[11] and contributed chapters to many books published by others;[12] [13] [14] [15] his work has been cited by a number of authors and researchers.[16] [17] [18] He was also associated with two journals, Journal of Biosciences and Molecular and Cellular Endocrinology as a member of their editorial boards.
Adiga died on 13 September 2006, at the age of 71, survived by his wife and two daughters.
Awards and honors
Adiga won the Giri Memorial Medal of the Indian Institute of Science in 1963, for his PhD thesis. The Council of Scientific and Industrial Research awarded him Shanti Swarup Bhatnagar Prize, one of the highest Indian science awards, in 1980.[19] Two years later, he received the Sanjay Gandhi Award for Science and Technology, the same year that he was elected as a fellow to the Indian Academy of Sciences.[20] The Society of Biological Chemists (India) awarded him the Professor M. Srinivasayya Award in 1984[21] and the Indian National Science Academy elected him as a fellow the same year.[22] His award orations include the Professor M. R. N. Prasad Memorial lecture of the Indian National Science Academy in 1992.[23]
Selected bibliography
Chapters
- Book: International Plant Genetic Resources Institute Staff. Lathyrus Genetic Resources Network. 1 December 1999. Bioversity International. 978-92-9043-394-1. 63–.
- Book: CIBA Foundation Symposium. Molecular Biology of Egg Maturation. 14 September 2009. John Wiley & Sons. 978-0-470-71849-0. 130–.
- Book: Satish Kumar Gupta. Reproductive Immunology. 6 December 2012. Springer Science & Business Media. 978-94-011-4197-0. 344–.
- Book: Arthur W. Galston. T.A. Smith. P. R. Adiga, G. L. Prasad. Polyamines in Plants. 6 December 2012. Springer Science & Business Media. 978-94-009-5171-6. Biosynthesis and regulation of polyamines in higher plants.
Articles
- Rao Saligame. L. K. Ramachandran. P. R. Adiga . The Isolation and Characterization of L-Homoarginine from Seeds of Lathyrus sativus . Biochemistry . 1963 . 2 . 2 . 298–300 . 10.1021/bi00902a019 . 1963. 13973060.
- K. Sivarama Sastry. Padmanaban Govindarajan. P. R. Adiga. P. S. Sarma . A sensitive microbiological assay procedure for determining magnesium in biological materials . The Analyst . 1963 . 88 . 1048 . 10.1039/an9638800534 . 1963 . 534. 1963Ana....88..534S.
- P. R. Adiga. P. S. Sarma. Rao Saligame . The Isolation and Characterization of β-N-Oxalyl-L-α,β-Diaminopropionic Acid: A Neurotoxin from the Seeds of Lathyrus sativus . Biochemistry . 1964 . 3 . 3 . 432–6 . 10.1021/bi00891a022 . 14155110 . 1964.
- P. R. Adiga. P. S. Sarma . Cysteine toxicity in Neurospora crassa: comparison of counteraction by sulphur amino acids and iron . Indian Journal of Biochemistry . 1970 . 1970 . 7 . 3 . 141–4. 4252565 .
- P. R. Adiga. P. S. Sarma . The influence of ribonucleic acid & some of its structural constituents on metal toxicities in Corcyra cephalonica St . Indian Journal of Biochemistry . 1970 . 1970 . 7 . 2 . 130–2. 4248650 .
See also
External links
- Web site: Browsing by Advisor Adiga, P R . 2017 . Indian Institute of Science . List of articles . 23 February 2017 . 24 February 2017 . https://web.archive.org/web/20170224052935/http://etd.ncsi.iisc.ernet.in/browse?type=advisor&order=ASC&rpp=20&value=Adiga,+P+R . dead .
Notes and References
- Web site: INSA Senior Scientist . 2017 . Indian National Science Academy . 23 February 2017 . 24 February 2017 . https://web.archive.org/web/20170224131755/http://insaindia.res.in/name1.php . dead .
- Web site: Endowed chairs for the Faculty . 2017 . Indian Institute of Science.
- Web site: Brief Profile of the Awardee . 2017 . Shanti Swarup Bhatnagar Prize.
- Web site: Fellow profile . 2016 . Indian Academy of Sciences.
- Web site: Deceased fellow . 2017-11-08 . Indian National Science Academy . 2017-11-08.
- Web site: View Bhatnagar Awardees . Shanti Swarup Bhatnagar Prize . 2016 . 12 November 2016.
- Web site: P. R. Adiga (1935–2006) . N. Appaji Rao . 2006 . Current Science . 1573–1574 . 23 February 2017 . 24 February 2017 . https://web.archive.org/web/20170224131651/http://www.iisc.ernet.in/currsci/dec102006/1573.pdf . dead .
- Web site: Handbook of Shanti Swarup Bhatnagar Prize Winners . Council of Scientific and Industrial Research . 1999 . 23 February 2017 . https://web.archive.org/web/20160304043957/http://www.csirhrdg.res.in/ssb.pdf . 4 March 2016 . dead .
- Web site: On ResearchGate . 2016 .
- Web site: Browse by Fellow . 2016 . Indian Academy of Sciences.
- Book: Perspectives In Primate Reproductive Biology . N.R. Moudgal . K. Yoshinaga . A.J. Rao . P.R. Adiga . Wiley Eastern . 1991 . 8122403182 . 364 . 23 February 2017 . 16 December 2017 . https://web.archive.org/web/20171216201152/http://library.kyu.ac.ug/cgi-bin/koha/opac-detail.pl?biblionumber=39214 . dead .
- Book: CIBA Foundation Symposium. Molecular Biology of Egg Maturation. 14 September 2009. John Wiley & Sons. 978-0-470-71849-0. 130–.
- Book: Satish Kumar Gupta. Reproductive Immunology. 6 December 2012. Springer Science & Business Media. 978-94-011-4197-0. 344–.
- Book: International Plant Genetic Resources Institute Staff. Lathyrus Genetic Resources Network. 1 December 1999. Bioversity International. 978-92-9043-394-1. 63–.
- Book: Arthur W. Galston. T.A. Smith. P. R. Adiga, G. L. Prasad. Polyamines in Plants. 6 December 2012. Springer Science & Business Media. 978-94-009-5171-6. Biosynthesis and regulation of polyamines in higher plants.
- Book: Krishnamurti Dakshinamurti. Vitamin Receptors: Vitamins as Ligands in Cell Communication - Metabolic Indicators. 21 July 1994. Cambridge University Press. 978-0-521-39280-8. 173–.
- Book: Tarun K. Ghose. Purnendu Ghosh. Biotechnology in India II. 3 July 2003. Springer. 978-3-540-36466-5. 213–.
- Book: Robert D. Slocum. Hector E. Flores. Biochemistry and Physiology of Polyamines in Plants. registration. 20 December 1991. CRC Press. 978-0-8493-6865-3. 21–.
- Web site: Medical Sciences . 2017 . Council of Scientific and Industrial Research . dead . https://web.archive.org/web/20130224074105/http://www.csir.res.in/External/Heads/career/award/BPRIZE/Medical_SCIENCES.htm . 2013-02-24 .
- Web site: IAS fellowship . 2017 . IndNet . 23 February 2017 . 22 February 2017 . https://web.archive.org/web/20170222210530/http://www.indnet.org/ias/Contents/Fellowship/Fellows/k-index.html . dead .
- Web site: M. Srinivasayya Award . 2017 . Society of Biological Chemists, India . 23 February 2017 . https://web.archive.org/web/20170224131439/http://iiscp.iisc.ernet.in/sbci/smaward.html . 24 February 2017 . dead . dmy-all .
- Web site: INSA Year Book 2016 . 2017 . Indian National Science Academy . 23 February 2017 . https://web.archive.org/web/20161104001952/http://www.insaindia.res.in/pdf/YearBook_2016.pdf . 4 November 2016 . dead .
- Web site: Professor M. R. N. Prasad Memorial lecture . 2017 . Indian National Science Academy.