Finegoldia Explained

Finegoldia is a genus of Gram-positive bacteria. They are anaerobic cocci of the class Clostridia, with Finegoldia magna being the type species.[1] F. magna was formerly known, along with several other Gram-positive anaerobic cocci (GPACs), as Peptostreptococcus magnus, but was moved into its own genus in 1999.[2] [3] The name is in honor of Sydney M. Finegold, an American microbiologist, while magna is Latin for large. It is an opportunistic human pathogen that normally colonizes skin and mucous membranes.[4] It is often seen in biofilms on chronic ulcers such as in diabetic foot or decubitus ulcers. Most surveys have found it to be susceptible to penicillins, carbapenems and metronidazole, though resistant strains have been identified.[5] Resistance to clindamycin is common and has been seen in over 10% of isolates in the US.[6] One review stated that "the combination of diminished antimicrobial susceptibility, its prevalence, and the described virulence factors gives F. magna a special position among the GPAC."

Notes and References

  1. Web site: Finegoldia. LPSN. 2016-01-06.
  2. Reclassification of Peptostreptococcus magnus (Prevot 1933) Holdeman and Moore 1972 as Finegoldia magna comb. nov. and Peptostreptococcus micros (Prevot 1933) Smith 1957 as Micromonas micros comb. nov.. Anaerobe. 1999-10-01. 555–559. 5. 5. 10.1006/anae.1999.0197. D. A. Murdoch. H. N. Shah.
  3. Book: Mandell, Douglas, and Bennett's principles and practice of infectious diseases. 978-1-4557-4801-3. Anaerobic Cocci and Anaerobic Gram-Positive Nonsporulating Bacilli. John e. Bennett. MD. Raphael Dolin. MD. Martin j. Blaser. MD. 2014-08-28.
  4. Finegoldia magna, not a well-known infectious agent of bacteriemic post-sternotomy mediastinitis. Anaerobe. 2015-04-01. 32–33. 32. 10.1016/j.anaerobe.2014.11.012. Claire. de Moreuil. Geneviève. Héry-Arnaud. Charles-Henri. David. Bastien. Provost. Philippe. Mondine. Zarrin. Alavi. Luc. de Saint Martin. Eric. Bezon. Rozenn Le. Berre. 25448620.
  5. Antimicrobial Susceptibility of Clinically Relevant Gram-Positive Anaerobic Cocci Collected over a Three-Year Period in the Netherlands. Antimicrobial Agents and Chemotherapy. 2011-03-01. 0066-4804. 3067104. 21189338. 1199–1203. 55. 3. 10.1128/AAC.01771-09. A. C. M.. Veloo. G. W.. Welling. J. E.. Degener.
  6. Antibiotic susceptibilities of Gram-positive anaerobic cocci: results of a sentinel study in England and Wales. Journal of Antimicrobial Chemotherapy. 2003-08-01. 0305-7453. 12837734. 224–228. 52. 2. 10.1093/jac/dkg316. J. S.. Brazier. V.. Hall. T. E.. Morris. M.. Gal. B. I.. Duerden. free.

This article is licensed under the GNU Free Documentation License. It uses material from the Wikipedia article "Finegoldia".

Except where otherwise indicated, Everything.Explained.Today is © Copyright 2009-2024, A B Cryer, All Rights Reserved. Cookie policy.