Peptidyl-prolyl cis-trans isomerase NIMA-interacting 4 explained

See also: Parvulin 14.

Peptidyl-prolyl cis-trans isomerase NIMA-interacting 4 is an enzyme that in humans is encoded by the PIN4 gene.^{[1] [2] [3]}

Further reading

• Uchida T, Fujimori F, Tradler T, etal . Identification and characterization of a 14 kDa human protein as a novel parvulin-like peptidyl prolyl cis/trans isomerase. . FEBS Lett. . 446 . 2–3 . 278–82 . 1999 . 10100858 . 10.1016/S0014-5793(99)00239-2 . 45172611 . free . 1999FEBSL.446..278U .
• Rulten S, Thorpe J, Kay J . Identification of eukaryotic parvulin homologues: a new subfamily of peptidylprolyl cis-trans isomerases . Biochem. Biophys. Res. Commun. . 259 . 3 . 557–62 . 1999 . 10364457 . 10.1006/bbrc.1999.0828 .
• Sekerina E, Rahfeld JU, Müller J, etal . NMR solution structure of hPar14 reveals similarity to the peptidyl prolyl cis/trans isomerase domain of the mitotic regulator hPin1 but indicates a different functionality of the protein . J. Mol. Biol. . 301 . 4 . 1003–17 . 2000 . 10966801 . 10.1006/jmbi.2000.4013 .
• Terada T, Shirouzu M, Fukumori Y, etal . Solution structure of the human parvulin-like peptidyl prolyl cis/trans isomerase, hPar14 . J. Mol. Biol. . 305 . 4 . 917–26 . 2001 . 11162102 . 10.1006/jmbi.2000.4293 .
• Suzuki Y, Tsunoda T, Sese J, etal . Identification and characterization of the potential promoter regions of 1031 kinds of human genes . Genome Res. . 11 . 5 . 677–84 . 2001 . 11337467 . 10.1101/gr.gr-1640r . 311086 .
• Fujiyama S, Yanagida M, Hayano T, etal . Isolation and proteomic characterization of human Parvulin-associating preribosomal ribonucleoprotein complexes . J. Biol. Chem. . 277 . 26 . 23773–80 . 2002 . 11960984 . 10.1074/jbc.M201181200 . free .
• Surmacz TA, Bayer E, Rahfeld JU, etal . The N-terminal basic domain of human parvulin hPar14 is responsible for the entry to the nucleus and high-affinity DNA-binding . J. Mol. Biol. . 321 . 2 . 235–47 . 2002 . 12144781 . 10.1016/S0022-2836(02)00615-0 .
• Strausberg RL, Feingold EA, Grouse LH, etal . Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences . Proc. Natl. Acad. Sci. U.S.A. . 99 . 26 . 16899–903 . 2003 . 12477932 . 10.1073/pnas.242603899 . 139241 . 2002PNAS...9916899M . free .
• Reimer T, Weiwad M, Schierhorn A, etal . Phosphorylation of the N-terminal domain regulates subcellular localization and DNA binding properties of the peptidyl-prolyl cis/trans isomerase hPar14 . J. Mol. Biol. . 330 . 5 . 955–66 . 2003 . 12860119 . 10.1016/S0022-2836(03)00713-7 .
• Gerhard DS, Wagner L, Feingold EA, etal . The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC) . Genome Res. . 14 . 10B . 2121–7 . 2004 . 15489334 . 10.1101/gr.2596504 . 528928 .

Notes and References

1. Mueller JW, Kessler D, Neumann D, Stratmann T, Papatheodorou P, Hartmann-Fatu C, Bayer P . Characterization of novel elongated Parvulin isoforms that are ubiquitously expressed in human tissues and originate from alternative transcription initiation . BMC Mol Biol . 7. 9 . Mar 2006 . 16522211 . 1420321 . 10.1186/1471-2199-7-9 . free .
2. Kessler D, Papatheodorou P, Stratmann T, Dian EA, Hartmann-Fatu C, Rassow J, Bayer P, Mueller JW . The DNA binding parvulin Par17 is targeted to the mitochondrial matrix by a recently evolved prepeptide uniquely present in Hominidae . BMC Biol . 5. 37 . Oct 2007 . 17875217 . 2031878 . 10.1186/1741-7007-5-37 . free .
3. Web site: Entrez Gene: PIN4 protein (peptidylprolyl cis/trans isomerase) NIMA-interacting, 4 (parvulin).