Pentarane A Explained

Pentarane A, also known as D'6-pentarane or pregna-D'6-pentarane, as well as 16α,17α-cyclohexanoprogesterone, 16α,17α-tetramethylenepregn-4-ene-3,20-dione, or 17α-acetyl-16β,24-cyclo-21-norchol-4-en-3-one, is a steroidal progestin that was developed by the Zelinskii Institute of Organic Chemistry of the Russian Academy of Sciences and was never marketed.[1] [2] The 6α-methylated analogue of pentarane A is known as mecigestone or as pentarane B.

See also

Notes and References

  1. Kamernitzky AV, Levina IS, Kulikova LE, Ignatov VN, Korkhov VV, Nikitina GV, Terekhina AI . Pregna-D'-pentaranes - a new class of active gestagenes . Journal of Steroid Biochemistry . 16 . 1 . 61–67 . January 1982 . 7062740 . 10.1016/0022-4731(82)90144-3 .
  2. Bhakta A, Herman M, Levina IS, Moudgil VK . Interaction of cycloalkanoprogesterones with mammalian progesterone receptor: binding of pregna-D'-pentaranes in the calf uterine cytosol . Molecular and Cellular Biochemistry . 125 . 2 . 153–161 . August 1993 . 8283970 . 10.1007/BF00936444 . 20319611 .

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