Penicillium parvum explained

Penicillium parvum is an anamorph species of fungus in the genus Penicillium which was isolated from soil in Papua New Guinea.^{[1] [2]} Penicillium parvum produces ferrichrome siderophores^{[3] [4]}

Phytochemical investigation of the soil microfungus Eupenicillum parvum led to the isolation of two new compounds: a chromone derivative euparvione and a new mycophenolic derivative euparvilactone, as well as thirteen known compounds. Several isolated compounds were evaluated for in vitro binding assays using opioid receptors (subtypes δ, κ, and μ) and cannabinoid receptors (CB1 and CB2). Compound 10 displayed the best selective μ-opioid receptor and CB1 receptor binding affinities showing values of 47% and 52% at a 10 μM concentration, respectively. These findings provide insight into the potential therapeutic utility of this class of compounds.^[5]

Further reading

• Book: Douglas Templeton . Molecular and Cellular Iron Transport Edition . CRC Press . 2002 . 0824744179.
• Book: T. R. Swinburne . Iron, Siderophores, and Plant Diseases . Springer Science & Business Media . 2012 . 1461594804.
• 10.5598/imafungus.2011.02.02.02. 22679596. Penicillium menonorum, a new species related to P. Pimiteouiense. IMA Fungus. 2. 2. 121. 2011. Peterson . S. W. . Orchard . S. S. . Menon . S. . 3359809.

Notes and References

1. http://www.lgcstandards-atcc.org/products/all/28050.aspx?geo_country=de ATCC
2. Book: Hakkō Kenkyūjo . List of cultures: microorganisms . The Institute . 2000 . 4891140100.
3. Book: Rajeev K. Upadhyay . K.G. Mukerji . B. P. Chamola . Biocontrol Potential and its Exploitation in Sustainable Agriculture: Volume 1: Crop Diseases, Weeds, and Nematodes . Springer Science & Business Media . 2001 . 0306464608.
4. Book: B.H. Dunford . D. Dolphin . K.N. Raymond . L. Sieker . The Biological Chemistry of Iron: A Look at the Metabolism of Iron and Its Subsequent Uses in Living Organisms Proceedings of the NATO Advanced Study Institute held at Edmonton, Alberta, Canada, August 13 – September 4, 1981 . Springer Science & Business Media . 2012 . 9400978820.
5. León. Francisco. Gao. Jiangtao. Dale. Olivia. Wu. Yunshan. Habib. Eman. Husni. Afeef. Hill. Robert. Cutler. Stephen. 2013-11-28. Secondary Metabolites from Eupenicillium parvum and Their in Vitro Binding Affinity for Human Opioid and Cannabinoid Receptors. Planta Medica. en. 79. 18. 1756–1761. 10.1055/s-0033-1351099. 0032-0943.