Penetrating atherosclerotic ulcer explained

Penetrating atherosclerotic ulcer
Field:Cardiology
Causes:Atherosclerosis
Diagnosis:MRI

A penetrating atherosclerotic ulcer (PAU) is an atherosclerotic lesion that ulcerates, leading to a hematoma forming within the walls of the aorta.[1]

Diagnosis

The condition is often associated with thickening of the aortic wall, and can be differentiated from similar conditions (atherosclerotic plaque and a thrombus) through the use of computed tomography and magnetic resonance imaging, though the latter is superior.[2] Transesophageal echocardiography and intravascular ultrasonography may also be used in differentiation.[1]

Treatment

Complications such as rupture or other life-threatening conditions are rare. Treatment may involve surgery, particularly when signs indicating worsening are present (the patient is unable to control their pain or changes in blood pressure).[1]

Notes and References

  1. Hayashi H, Matsuoka Y, Sakamoto I, etal . Penetrating atherosclerotic ulcer of the aorta: imaging features and disease concept . Radiographics . 20 . 4 . 995–1005 . 2000 . 10903689 . 10.1148/radiographics.20.4.g00jl01995.
  2. Chu . B . Yuan C . Takaya N . Serial high-spatial-resolution, multisequence magnetic resonance imaging studies identify fibrous cap rupture and penetrating ulcer into carotid atherosclerotic plaque . Circulation . American Heart Association . 113 . 12 . e660–e661 . March 2006 . 16567574 . 10.1161/CIRCULATIONAHA.105.567255 . 2008-05-28 . etal. free .