Pendetide Explained

Pendetide (GYK-DTPA) is a chelating agent. It consists of pentetic acid (DTPA) linked to the tripeptide glycine (G) – L-tyrosine (Y) – L-lysine (K).[1]

Use

The following monoclonal antibodies are linked to pendetide to chelate a radionuclide, indium-111. The antibodies selectively bind to certain tumour cells, and the radioactivity is then used for imaging of the tumours.

Notes and References

  1. https://web.archive.org/web/20040627024748/http://whqlibdoc.who.int/inn/proposed_lists/prop_INN_list67.pdf WHO Drug Information