| Official Name: | Pence, Indiana |
| Settlement Type: | Unincorporated community and Census-designated place |
| Pushpin Map: | USA Indiana Warren County#Indiana#USA |
| Pushpin Label: | Pence |
| Subdivision Type: | Country |
| Subdivision Name: | United States |
| Subdivision Type1: | State |
| Subdivision Name1: | Indiana |
| Subdivision Type2: | County |
| Subdivision Name2: | Warren |
| Subdivision Type3: | Township |
| Subdivision Name3: | Jordan |
| Established Title: | Founded |
| Established Date: | 1902 |
| Founder: | Frank R. Pence |
| Area Total Sq Mi: | 0.17 |
| Population As Of: | 2020 |
| Population Total: | 41 |
| Timezone: | Eastern (EST) |
| Utc Offset: | -5 |
| Timezone Dst: | EDT |
| Utc Offset Dst: | -4 |
| Coordinates: | 40.3636°N -87.5128°W |
| Elevation Ft: | 689 |
| Postal Code Type: | ZIP code |
| Postal Code: | 47993 |
| Area Code: | 765 |
| Blank Name: | GNIS feature ID |
| Blank Info: | 2806540 |
| Unit Pref: | Imperial |
| Area Footnotes: | [1] |
| Area Land Km2: | 0.44 |
| Area Land Sq Mi: | 0.17 |
| Population Density Sq Mi: | 242.60 |
| Population Density Km2: | 93.56 |
Pence is a small unincorporated community in Jordan Township, Warren County, in the U.S. state of Indiana.
Pence was founded in September 1902 by Frank R. Pence, who purchased 40acres of land for the purpose. In 1903, Pence became the smallest town in the United States to have a central water system. In the early part of the 20th century, Pence had numerous businesses including a grain elevator, a blacksmith shop, a welding and machine shop, a lumber yard, a coal yard, the Bank of Pence (which closed in the 1920s), a hotel (which also housed the post office for a time), restaurants, a general store, grocery stores, a hardware store, a weekly newspaper, a funeral home, a jewelry store, and various others. As of 1913, the population was about 150.[2]
Pence had a baseball team from 1910 to 1955, and also had a basketball team (the Pence Aces).
The post office operated from October 12, 1903 to April 5, 1957.
Pence is located less than a mile east of the Indiana-Illinois state line and a quarter mile from Jordan Creek, which flows southwest toward the Vermilion River. It is on County Road 300 North, which (in Illinois) runs into the town of Rossville about 9 miles to the west.