| Honorific-Prefix: | Most Reverend |
| Pedro Manuel | |
| Archbishop of Santiago de Compostela | |
| Church: | Catholic Church |
| Archdiocese: | Archdiocese of Santiago de Compostela |
| Term: | 1546–1550 |
| Predecessor: | Gaspar de Ávalos de la Cueva |
| Successor: | Juan Álvarez de Toledo |
| Death Date: | 1 January 1550 |
| Death Place: | Santiago de Compostela, Spain |
| Previous Post: | Bishop of León (1523–1534) Bishop of Zamora (1534–1546) |
Pedro Manuel (died 1 January 1550) was a Roman Catholic prelate who served as Archbishop of Santiago de Compostela (1546 - 1550), Bishop of Zamora (1534 - 1546), and Bishop of León (1523 - 1534).[1]
On 12 June 1523, Pedro Manuel was appointed during the papacy of Pope Adrian VI as Bishop of León. On 17 June 1534, he was appointed during the papacy of Pope Clement VII as bishop of Zamora. On 9 April 1546, Pedro Manuel was appointed during the papacy of Pope Paul III as Archbishop of Santiago de Compostela. He served as Archbishop of Santiago de Compostela until his death on 1 January 1550. While bishop, he was the principal consecrator of Juan González Munébraga, Bishop of Tarazona (1547).