| Official Name: | Peñausende |
| Pushpin Map: | Spain |
| Pushpin Map Caption: | Location in Spain. |
| Subdivision Name3: | Sayago |
| Leader Title: | Mayor |
| Leader Name: | Manuel Alfonso Rivera Sastre |
| Area Total Km2: | 95.02 |
| Elevation M: | 872 |
| Population Demonym: | Peñausendino |
| Population Density Km2: | auto |
| Utc Offset: | +1 |
| Utc Offset Dst: | +2 |
| Coordinates: | 41.2864°N -5.3675°W |
Peñausende (pronounced as /es/) is a municipality located in the province of Zamora, Castile and León, Spain.