| Pauline May Harrison | |
| Birth Date: | 24 August 1926 |
| Fields: | Biology, crystallography |
| Workplaces: | University of Sheffield |
| Alma Mater: | Somerville College, Oxford |
| Thesis Title: | X-Ray crystallographic studies in some peptides and proteins |
| Thesis Year: | 1952 |
| Doctoral Advisor: | Dorothy Hodgkin |
| Known For: | Protein crystallography of ferritin |
| Awards: | CBE, DSc |
| Spouse: | Royden Harrison |
Pauline May Harrison (née Cowan, 24 August 1926 – 28 May 2024) was a British protein crystallographer and professor emeritus at the University of Sheffield. She gained her chemistry degree from Somerville College, Oxford in 1948, followed by a DPhil in X-ray crystallography in 1952 supervised by Dorothy Hodgkin. After three years at King's College London (contemporary with Rosalind Franklin) she moved to the University of Sheffield in 1955 as a demonstrator in the Biochemistry department (now Molecular Biology and Biotechnology), obtaining an MRC grant to study the iron storage protein Ferritin, publishing preliminary X-ray diffraction data in the 1st volume of the Journal of Molecular Biology in 1959. The molecule which became her life's work. In 1978, she was awarded a personal chair and retired in 1991. In 2001 she was appointed a CBE for services to higher education.
Harrison was the daughter of botanists Adeline May Organe and John Macqueen Cowan, Assistant Keeper of the Royal Botanic Garden, Edinburgh. She was married to Royden Harrison, also a lecturer at Sheffield and a figure in the Labour movement until his death in 2002. Harrison was an alumna of St. Trinnean's School.
Harrison died on 28 May 2024, at the age of 97.[1]