| Paula T. Hammond | |
| Birth Date: | 3 September 1963 |
| Birth Place: | Detroit, Michigan, United States |
| Nationality: | American |
| Fields: | Biomaterials, Drug Delivery, Cancer immunology |
| Workplaces: | Massachusetts Institute of Technology |
| Alma Mater: | Massachusetts Institute of Technology Georgia Institute of Technology |
| Thesis Title: | The Synthesis, Characterization and Optical Properties of Novel Diacetylene-Containing Aromatic Liquid Crystalline Polymers |
| Thesis Url: | http://hdl.handle.net/1721.1/109630 |
| Thesis Year: | 1993 |
| Doctoral Advisor: | Michael Rubner |
| Academic Advisors: | George M. Whitesides |
| Doctoral Students: | Jodie Lutkenhaus LaShanda Korley |
| Awards: | Fellow of the National Academy of Inventors (2021), Fellow of the National Academy of Sciences (2019), Fellow of the National Academy of Engineering (2017), Fellow of the National Academy of Medicine (2016), Fellow of the American Institute of Chemical Engineers (2016), Fellow of the American Academy of Arts and Sciences (2013) |
| Website: | https://hammondlab.mit.edu/ |
Paula Therese Hammond (born September 3, 1963) is an Institute Professor[1] and the Vice Provost for Faculty[2] at the Massachusetts Institute of Technology (MIT). She was the first woman and person of color appointed as head of the Chemical Engineering department.[3] Her laboratory designs polymers and nanoparticles for drug delivery and energy-related applications including batteries and fuel cells.
Hammond has been the recipient of numerous awards and is a member of the National Academy of Medicine (2016),[4] the National Academy of Engineering (2017, “for contributions to self-assembly of polyelectrolytes, colloids, and block copolymers at surfaces and interfaces for energy and healthcare applications”),[5] the National Academy of Sciences (2019),[6] and the National Academy of Inventors (2021).[7]
She is an intramural faculty member of the Koch Institute for Integrative Cancer Research and an Associate Editor of ACS Nano.[8] [9]
Hammond was born in 1963 in Detroit, Michigan[10] as Paula Therese Goodwin to parents Jesse Francis and Della Mae Goodwin (née McGraw). Her father has a Ph.D in Biochemistry and her mother has a master's degree in nursing.[11]
Goodwin graduated a year prior to her expected date at the Academy of the Sacred Heart in Bloomfield, Michigan in 1980.[12] After graduation, Goodwin went on to study and earn a Bachelor of Science in Chemical Engineering from Massachusetts Institute of Technology (MIT) in 1984. After completing her bachelors, she went to work for Motorola for two years as a process engineer in the packaging of integrated circuits. She returned to academia and obtained a Master of Science in chemical engineering from the Georgia Institute of Technology in 1988, while working at Georgia Tech Research Institute as a research engineer.[13] Hammond's master's thesis was on conducting elastomers for robotic tactile sensors.[14]
In 1988, she returned to MIT to earn her Ph.D. in chemical engineering (granted in 1993). At MIT she worked under the supervision of Michael F. Rubner. Her Ph.D. thesis research focused on synthesizing polymers with mechanochromic properties. After completing her Ph.D., Hammond was a NSF Postdoctoral Fellow with George M. Whitesides in the chemistry department at Harvard University.
In 1995 Hammond was appointed to Massachusetts Institute of Technology as an Assistant Professor. Hammond and her lab uses understanding of secondary interactions to guide materials assembly at surfaces and in solution to design polymers and nanoparticles for applications in drug delivery; wound healing; and energy and fuel cells.[15] [16] Her work involves Layer by layer (LbL) assembly, which builds films of alternating positively and negatively charged molecules.[17] Additionally, her lab works with nanoparticle drug carriers for targeted nanoparticle drug, gene, and siRNA delivery for cancer treatment as well as artificial polypeptides and polymeric nucleic acids to engage biology and build novel drug systems.
Hammond has developed "stealth polymers" to disguise cancer chemotherapeutics contained in nanoparticles so that they can reach tumors.[18] She also works on ways to transport RNA into cells to either increase[19] or decrease the expression of specific genes.[20]
Hammond cofounded MIT's Institute for Soldier Nanotechnology, a partnership between MIT, the Army, and industry partners to develop nanotechnology to improve soldier "protection and survivability."[21] [22] As part of this program, Hammond designed a spray that helps blood clot to prevent blood loss.
Hammond developed LayerForm™️ technology to build drug delivery films with alternating drug and polymer layers. In 2013, she co-founded a biotechnology company, LayerBio Inc. to commercialize LayerForm™️ for regenerative medicine applications.[23]
Hammond is a member of the board of directors for Alector, a biotech company focusing on immuno-neurology.[24] She is also a member of the board of director for Burroughs Wellcome Fund.[25]
Hammond also works on the development of polymers for use in batteries thin films of carbon microtubules that can be used in batteries, solar cells, and fuel cells.[26] She presented research on virus-based batteries to Barack Obama in 2009.
Hammond has received multiple honors and awards throughout her career. As a graduate student in 1992, she was awarded a Ford Foundation Dissertation Fellowship from the National Academy of Sciences.[27] Her postdoc was supported by an NSF Postdoctoral Fellowship in Chemistry, awarded in 1994. Since joining the faculty at MIT, Hammond has amassed several plaudits, with early career highlights including an Environmental Protection Agency Early Career Research Award[28] in 1996 and an NSF CAREER Award for Young Investigators[29] in 1997. In 2013, Hammond was one of three African-American female fellows to be elected to the American Academy of Arts and Sciences. She was elected to the National Academy of Medicine[30] and the National Academy of Engineering[31] in rapid succession in 2016 and 2017, respectively, the National Academy of Sciences[32] in 2019 and finally the National Academy of Inventors in 2021. In 2021 Hammond was also selected to be a member of the President's Council of Advisors on Science and Technology (PCAST) under President Biden.[33] In 2024, Hammond was awarded the Benjamin Franklin Medal in Chemistry for innovative methods to create novel materials one molecular layer at a time and for applying these materials to areas ranging from drug delivery to energy storage.[34]