Patrik Rorsman Explained

Patrik Rorsman
Birth Date:1959 5, df=yes
Birth Place:Lund, Sweden
Nationality:Swedish
Alma Mater:Uppsala University (PhD)
Thesis Title:Patch-clamp studies on pancreatic glucagon- and insulin-secreting cells
Thesis Url:http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-114628
Thesis Year:1986
Doctoral Advisor:Bert Sakmann

Patrik Rorsman (born 1959) FRS FMedSci is Professor of Diabetic Medicine at the Oxford Centre for Diabetes, Endocrinology and Metabolism (OCDEM), in the Radcliffe Department of Medicine at the University of Oxford[1] and a fellow of Harris Manchester College, Oxford.[2] [3]

Education

Rorsman was educated at Uppsala University in Sweden where he was awarded a PhD under the supervision of Nobel laureate Bert Sakmann in 1986 for patch clamp studies of pancreatic cells and their secretion of glucagon and insulin.[4]

Career

Rorsman was for short time the Canadian Excellence in Research Chair (CERC) in Diabetes[1] [5] [6] at the University of Alberta in Edmonton, before being reappointed a Professor at the University of Oxford in 2011.[1]

Research

Rorsman's research investigates exocytosis, ion channels and diabetes mellitus type 2.[7] [8] [9] [10] [11] [12] [13] [14] [15] His research been funded by the Medical Research Council (MRC),[16] the Royal Society, the Wolfson Foundation, the Knut and Alice Wallenberg Foundation,[17] the Wellcome Trust and the Government of Canada.[3]

Awards and honours

Rorsman was elected a Fellow of the Royal Society (FRS) in 2014. His nomination reads:

Rorsman was elected a Fellow of the Academy of Medical Sciences (FMedSci) in 2010. His nomination reads:

Rorsman was awarded the Minkowski Prize in 1996, the Göran Gustafsson Prize in 2003 and the Albert Renold Prize in 2013.

Notes and References

  1. 10.1038/nj7428-301a. Turning point: Patrik Rorsman. Nature. 492. 7428. 301. 2012. Gewin . V. . free.
  2. http://www.hmc.ox.ac.uk/pages/default.asp?id=16&sID=86&cP=298 Professor Patrik Rorsman, Harris Manchester College
  3. http://news.nationalpost.com/2012/11/14/they-suffer-from-the-climate-research-scientist-leaves-10m-edmonton-research-grant-behind-returns-to-england/ Patrik Rorsman leaves $10M Edmonton research grant behind, returns to England
  4. PhD . Patrik. Rorsman . Patch-clamp studies on pancreatic glucagon- and insulin-secreting cells . Uppsala University. 1986 . Patrik Rorsman.
  5. https://labandfield.wordpress.com/2013/05/06/the-value-of-the-canada-excellence-research-chairs-cerc-program/ The value of the Canada Excellence Research Chairs (CERC) program
  6. , University of Alberta
  7. 10.1016/0079-6107(89)90013-8. Electrophysiology of the pancreatic β-cell. Progress in Biophysics and Molecular Biology. 54. 2. 87–143. 1989. Ashcroft . F. M. . Frances Ashcroft. Rorsman . P. . Patrik Rorsman. 2484976. free.
  8. 10.1038/nature03076. A pancreatic islet-specific microRNA regulates insulin secretion. Nature. 432. 7014. 226–30. 2004. Poy . M. N. . Eliasson . L. . Krutzfeldt . J. . Kuwajima . S. . Ma . X. . MacDonald . P. E. . Pfeffer . S. B. . Tuschl . T. . Rajewsky . N. . Rorsman . P. . Stoffel . M. . 15538371. 2004Natur.432..226P. 4415988.
  9. 10.1007/s00125-003-1153-1. Insulin granule dynamics in pancreatic beta cells. Diabetologia. 46. 8. 1029–45. 2003. Rorsman . P.. Renstrom . E.. 12879249. free.
  10. 10.1038/363356a0. Calcium-independent potentiation of insulin release by cyclic AMP in single β-cells. Nature. 363. 6427. 356–358. 1993. Ämmälä . C. . Ashcroft . F. M. . Rorsman . P. . 7684514. 1993Natur.363..356A. 4341009.
  11. 10.1038/341233a0. Glucose-inhibition of glucagon secretion involves activation of GABAA-receptor chloride channels. Nature. 341. 6239. 233–6. 1989. Rorsman . P. . Berggren . P. O. . Bokvist . K. . Ericson . H. . Möhler . H. . Östenson . C. G. R. . Smith . P. A. . 2550826. 1989Natur.341..233R. 699135.
  12. 10.1098/rstb.2005.1762. Glucose-sensing mechanisms in pancreatic -cells. Philosophical Transactions of the Royal Society B: Biological Sciences. 360. 1464. 2211–25. 2005. MacDonald . P. E.. Joseph . J. W.. Rorsman . P.. 1569593 . 16321791.
  13. Gerken . T. . Girard . C. A. . Tung . Y. -C. L. . Webby . C. J. . Saudek . V. . Hewitson . K. S. . Yeo . G. S. H. . McDonough . M. A. . Cunliffe . S. . McNeill . 10.1126/science.1151710 . L. A. . Galvanovskis . J. . Rorsman . P. . Patrik Rorsman. Robins . P. . Prieur . X. . Coll . A. P. . Ma . M. . Jovanovic . Z. . Farooqi . I. S.. Sadaf Farooqi . Sedgwick . B. . Barroso . I. . Lindahl . T. . Tomas Lindahl. Ponting . C. P. . Chris Ponting. Ashcroft . F. M. . Frances Ashcroft. O'Rahilly . S. . Stephen O'Rahilly. Schofield . C. J. . Christopher J. Schofield . The Obesity-Associated FTO Gene Encodes a 2-Oxoglutarate-Dependent Nucleic Acid Demethylase . Science . 318 . 5855 . 1469–1472 . 2007 . 17991826. 2668859 . 2007Sci...318.1469G .
  14. , University of Oxford
  15. , Scandinavian Physiological Society
  16. http://gtr.rcuk.ac.uk/person/5ADEBA84-AFD6-4FAC-B1B6-16B2436E5CBA UK Government research grants awarded to Patrik Rorsman
  17. http://www.akademiliv.se/en/2012/12/9066/ Wallenberg researcher aiming to solve the riddle of diabetes

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