Patricia Zambryski Explained

Other Names:	Patricia C. Zambryski O'Farrell
Workplaces:	University of California, Berkeley
Alma Mater:	University of Colorado
Thesis Title:	The Regulation of gene expression during bacteriophage T4 development
Thesis Url:	https://www.worldcat.org/oclc/
Thesis Year:	1974

Patricia C. Zambryski is a plant and microbial scientist known for her work on Type IV secretion and cell-to-cell transport in plants. She is also professor emeritus at the University of California, Berkeley.^[1]

She was an elected member of the National Academy of Sciences, the American Association for the Advancement of Science, and the American Society for Microbiology.

Education and career

Zambryski received her B.S. from McGill University in 1969, and earned a Ph.D. from the University of Colorado in 1974.^{[2] [3]}

Research

Zambryski is known for her work in the field of genetic engineering, specifically for her work with Agrobacterium tumefaciens, a bacterium she uses to track the molecular mechanisms that change plants and how plant cells communicate with each other. She has examined the structure of plant cells that have been altered by Agrobacterium tumefaciens.^[4] While working in Marc Van Montagu's lab, Zambryski determined how the Ti plasmid is identified by the bacterium, and she developed a vector that allowed the transfer of genetic material into a plant without altering the plant tissue.^{[5] [6]} This advance was used to inject novel genes into plants.^[7] She has also examined plasmodesmata, which are the channels that reach across the spaces in plant cells.^{[8] [9]}

Selected publications

• Zambryski . P. . Joos . H. . Genetello . C. . Leemans . J. . Van Montagu . M. . Schell . J. . 1983 . Ti plasmid vector for the introduction of DNA into plant cells without alteration of their normal regeneration capacity . The EMBO Journal . en . 2 . 12 . 2143–2150 . 10.1002/j.1460-2075.1983.tb01715.x. 16453482 . 555426 .
• Stachel . Scott E. . Messens . Eric . Van Montagu . Marc . Zambryski . Patricia . 1985 . Identification of the signal molecules produced by wounded plant cells that activate T-DNA transfer in Agrobacterium tumefaciens . Nature . en . 318 . 6047 . 624–629 . 10.1038/318624a0 . 1985Natur.318..624S . 4287289 . 0028-0836.
• Baker . Barbara . Zambryski . Patricia . Staskawicz . Brian . Dinesh-Kumar . S. P. . 1997-05-02 . Signaling in Plant-Microbe Interactions . Science . en . 276 . 5313 . 726–733 . 10.1126/science.276.5313.726 . 9115193 . 0036-8075.
• Zambryski . Patricia . Crawford . Katrina . 2000-11-01 . Plasmodesmata: Gatekeepers for Cell-to-Cell Transport of Developmental Signals in Plants . Annual Review of Cell and Developmental Biology . 16 . 1 . 393–421 . 10.1146/annurev.cellbio.16.1.393 . 11031242 . 1081-0706.
• Stachel . Scott E. . Zambryski . Patricia C. . 1986-08-01 . virA and virG control the plant-induced activation of the T-DNA transfer process of A. tumefaciens . Cell . English . 46 . 3 . 325–333 . 10.1016/0092-8674(86)90653-7 . 0092-8674 . 3731272. 37938846 .

Awards and honors

In 2001 she was elected a member of the National Academy of Sciences^[10] and a fellow of the American Society for Microbiology. In 2010 she was elected a fellow of the American Association for the Advancement of Science.

Notes and References

1. Web site: Patricia C. Zambryski . 2022-05-02 . Plant & Microbial Biology University of California, Berkeley . en.
2. Web site: 2016-03-16 . Patricia C. Zambryski Department of Plant & Microbial Biology UC Berkeley . 2022-05-02 . https://web.archive.org/web/20160316170108/https://plantandmicrobiology.berkeley.edu/profile/pzambryski . 2016-03-16 .
3. Book: Privalle, Laura S. . Women in Sustainable Agriculture and Food Biotechnology: Key Advances and Perspectives on Emerging Topics . 2017-03-08 . Springer . 978-3-319-52201-2 . 10–11 . en.
4. Zambryski . Patricia . Holsters . Marcelle . Kruger . Kelly . Depicker . Ann . Schell . Josef . Van Montagu . Marc . Goodman . Howard M. . 1980-09-19 . Tumor DNA Structure in Plant Cells Transformed by A. tumefaciens . Science . en . 209 . 4463 . 1385–1391 . 10.1126/science.6251546 . 6251546 . 1980Sci...209.1385Z . 0036-8075.
5. Book: Godwin, Ian D. . Good Enough to Eat?: Next Generation GM Crops . 2019-01-18 . Royal Society of Chemistry . 978-1-78801-681-0 . en.
6. Zambryski . P. . Joos . H. . Genetello . C. . Leemans . J. . Van Montagu . M. . Schell . J. . 1983 . Ti plasmid vector for the introduction of DNA into plant cells without alteration of their normal regeneration capacity . The EMBO Journal . en . 2 . 12 . 2143–2150 . 10.1002/j.1460-2075.1983.tb01715.x. 16453482 . 555426 .
7. Book: Schmeck, Harold M. . Gene-splicing of plants makes advance . Sarasota Herald-Tribune . October 6, 1983 . en.
8. Zambryski . Patricia . Crawford . Katrina . 2000 . Plasmodesmata: Gatekeepers for Cell-to-Cell Transport of Developmental Signals in Plants . Annual Review of Cell and Developmental Biology . en . 16 . 1 . 393–421 . 10.1146/annurev.cellbio.16.1.393 . 11031242 . 1081-0706.
9. Burch-Smith . Tessa M. . Zambryski . Patricia C. . 2012-06-02 . Plasmodesmata Paradigm Shift: Regulation from Without Versus Within . Annual Review of Plant Biology . 63 . 1 . 239–260 . 10.1146/annurev-arplant-042811-105453 . 22136566 . 1543-5008.
10. Web site: Patricia C. Zambryski . 2022-05-02 . www.nasonline.org.