| Patricia Santana | |
| Birth Place: | San Diego, California, U.S. |
| Occupation: | Novelist |
| Nationality: | American |
| Alma Mater: | University of California, San Diego University of California, Los Angeles |
| Awards: | Premio Aztlán Literary Prize (2008) American Book Award (2009) |
| Children: | 2 |
Patricia Santana (born 1955 San Diego) is a Latina American novelist.
She is the eighth of nine children of Mexican immigrants. Her parents are from El Grullo, Jalisco.
She graduated from the University of California, San Diego, and from the University of California, Los Angeles with a master's degree in Comparative Literature.
She is a Spanish instructor at Cuyamaca Community College and is also an occasional visiting lecturer at the University of California, San Diego, where she teaches creative writing.
She is the mother of Deborah and Isaac.