Patricia DeLeon explained
Patricia Anastastia Martin DeLeon |
Birth Place: | Port Maria |
Birth Date: | 13 July 1944 |
Thesis Title: | Chromosome studies of rabbit blastocysts resulting from spermatazoa [sic] aged in vivo |
Thesis Url: | http://www.worldcat.org/oclc/15774120 |
Thesis Year: | 1972 |
Patricia Anastastia Martin DeLeon (born 13 July 1944) is a Jamaican reproductive geneticist who is specialists in the male reproductive system. She is the Trustees Distinguished Professor of Biological Sciences at the University of Delaware. In 2010 she was awarded the Presidential Award for Excellence in Science, Mathematics, and Engineering Mentoring by Barack Obama.
Early life and education
DeLeon was born in Port Maria. She was one of nine children, and had to lobby the principal of her high school, Excelsior High School, to waive the fees to allow her family to attend. She became interested in botany as a child and learnt the Latin names of all the plants that she collected.[1] The principal agreed based on DeLeon's academic performance. She attended the University of the West Indies for her undergraduate studies, where she focussed on zoology and chemistry. After earning her undergraduate degree DeLeon moved to Canada, where she joined the University of Western Ontario for her doctoral degree in microscopic anatomy.[2] She was subsequently a postdoc at McGill University.
Research and career
In 1976 DeLeon joined the faculty at the University of Delaware.[3] DeLeon has extensively studied the Sperm adhesion molecule 1 (SPAM1), a glycosylphosphatidylinositol linked membrane protein. The mechanisms that underpin the expression of these proteins are poorly understood, but are crucial for the development of assisted reproductive technology.[4] The over-expression of SPAM1 can give rise to cancer. In 2009 she was named the Trustees Distinguished Professor of Biological Sciences.[5] Alongside her work on male fertility, DeLeon has studied particles in the fallopian tube, the understanding of which may improve the outcomes of in vitro fertilisation. She is working on non-invasive diagnostic methods to identify embryos that are most likely to result in successful IVF.[6]
Throughout her career DeLeon has worked to support undergraduates gain research experience.[7]
Awards and honours
Selected publications
- Martin-DeLeon. Patricia A.. 2006. Epididymal SPAM1 and its impact on sperm function. Molecular and Cellular Endocrinology. 250. 1–2. 114–121. 10.1016/j.mce.2005.12.033. 16420970. 25997623. 0303-7207.
- Al-Dossary. Amal A.. Strehler. Emanuel E.. Martin-DeLeon. Patricia A.. 2013-11-14. Expression and Secretion of Plasma Membrane Ca2+-ATPase 4a (PMCA4a) during Murine Estrus: Association with Oviductal Exosomes and Uptake in Sperm. PLOS ONE. 8. 11. e80181. 10.1371/journal.pone.0080181. 24244642. 3828235. 2013PLoSO...880181A. 1932-6203. free.
- Nigro, Janice M. Schweinfest, Clifford W. Rajkovic, Aleksandar Pavlovic, Jovan Jamal, Sumayah Dottin, Robert P. Hart, John T. Kamarck, Michael E. Rae, Peter M. M. Carty, Maynard D. Martin-Deleon, Patricia. cDNA cloning and mapping of the human creatine kinase M gene to 19q13. American Journal of Human Genetics. 1987. 40. 2. 115–25. 3031982. 1684079. 679561920.
Notes and References
- Nowak. Romana A.. 2018-11-01. An interview with Dr Patricia A. Martin-DeLeon. Biology of Reproduction. en. 99. 5. 899–902. 10.1093/biolre/ioy103. 30561557. 0006-3363. free.
- Web site: AlisonAwardDeLeon. 2020-08-02. www.bio.udel.edu. en-US.
- Web site: 2017-06-21. Patricia Martin-DeLeon. 2020-08-02. Icons. en-US.
- Web site: Patricia A. DeLeon, PhD. 2020-08-02. Careers in Andrology. en.
- Web site: Patricia DeLeon's Biography. 2020-08-02. The HistoryMakers. en.
- Web site: contributor. Joey Davidson /. 2017-01-13. This UD researcher hopes to make in vitro fertilization much more affordable. 2020-08-02. Technical.ly Delaware. en.
- Web site: PAESMEM » Awardee Profile. 2020-08-02. paesmem.net.
- Web site: American Society of Andrology . April 5, 2005 . ASA 30th Annual Meeting Program . May 23, 2023 . American Society of Andrology.
- Web site: Patricia Martin-DeLeon: Scientist par Excellence! Mona E-Connection. 2020-08-02. www.mona.uwi.edu.
- Web site: 2009-07-09. President Honors Outstanding Science, Math, Engineering Teachers and Mentors. 2020-08-02. whitehouse.gov. en.
- Web site: 11th William G. Demas Lecture. 2020-08-02. en-US.
- Web site: 50 Most Outstanding Jamaican Women - Record. 2020-08-02. calameo.com.