Parafluorofuranylfentanyl Explained

para-Fluorofuranylfentanyl (FFF, p-F-Fu-F) is an opioid analgesic that is an analog of fentanyl and has been sold as a designer drug.^[1] As with other fentanyl analogues, parafluorofuranylfentanyl has significant side effects including itching, nausea and potentially serious respiratory depression, which can be life-threatening, and it has been linked to numerous deaths from overdose.^[2] It falls within the definition of Schedule I drugs in the USA under federal drug analogue legislation, and is specifically listed as a Schedule I drug in North Dakota.^[3]

See also

• Furanylfentanyl
• Parafluorofentanyl
• List of fentanyl analogues

Notes and References

1. Vincenti F, Montesano C, Di Ottavio F, Gregori A, Compagnone D, Sergi M, Dorrestein P . Molecular Networking: A Useful Tool for the Identification of New Psychoactive Substances in Seizures by LC-HRMS . Frontiers in Chemistry . 8 . 572952 . 2020 . 33324608 . 7723841 . 10.3389/fchem.2020.572952 . free .
2. Rodriguez Salas J, Krotulski AJ, Newman R, Thogmartin JR, Mohr AL, Logan BK . Concentrations of para-Fluorofuranylfentanyl in Paired Central and Peripheral Blood Collected during Postmortem Death Investigations . Journal of Analytical Toxicology . 46 . 4 . 358–373 . April 2022 . 33693685 . 10.1093/jat/bkab025 .
3. Web site: AN ACT to amend and reenact sections 19-03.1-05, 19-03.1-11, and 19-03.1-13 of the North Dakota Century Code, relating to the scheduling of controlled substances; and to declare an emergency. . Sixty-eighth Legislative Assembly of North Dakota in Regular Session . 3 January 2023 .