List of paracetamol brand names explained

The medication paracetamol (INN) (or), also known as acetaminophen (USAN), is sold around the world under a number of different brand names. Common brand names include Tylenol, Excedrin, Calpol, and Panadol.

Tylenol

See main article: Tylenol (brand). Tylenol is a brand of drugs advertised for reducing pain, reducing fever, and relieving the symptoms of allergies, cold, cough headache, and influenza. The active ingredient of its original flagship product is paracetamol. The brand name "Tylenol" is owned by McNeil Consumer Healthcare,[1] a subsidiary of Kenvue. As of 2017 the brand was used in Brazil, Canada, China, Egypt, Lebanon, Myanmar, Oman, Philippines, Portugal, Switzerland, Thailand, United States, and Vietnam.[2]

Calpol

Calpol is a brand of children's medicine sold in the UK, Ireland, India, Cyprus, Hong Kong, Kenya, Malta, Philippines and Turkey. The main product is a paracetamol suspension, branded as Calpol Infant Suspension. It is usually a coloured syrup with a sweet taste, and is used to treat fever and pain. In 2016 it was the second biggest selling branded over-the-counter medication sold in Great Britain, with sales of £66.3 million.[3]

Calpol also comes in a form containing ibuprofen, marketed under the name Calprofen. Calpol is a common cause of accidental child poisoning because of its pleasant taste.[4] Calpol Night, a product containing paracetamol and an antihistamine, was listed for use from 2+ months. However, this was changed and it is now only considered suitable for children over the age of 6 years.[5]

History

Calpol was launched in 1959 by English pharmaceutical company, Calmic Ltd, based in Crewe, Cheshire; the company's name was an abbreviation of Cheshire and Lancashire Medical Industries Corporation, which moved from Lancashire to Crewe Hall in 1947.[6] The Calpol brand name is likely a combination of 'Calmic' and 'paracetamol'. Calmic was acquired by Wellcome (today GlaxoSmithKline) in 1966, and Calpol became one of Wellcome's best-selling UK products in the 1980s.[7] The brand was later owned by Pfizer Consumer Healthcare, which was acquired by Johnson & Johnson in 2006.[8] Calpol is today a brand of Johnson & Johnson's McNeil Consumer Healthcare subsidiary; in 2020, Calpol was the UK's top-selling paediatric analgesic product with sales worth £60.1 million.[9]

Panadol

Panadol is one of Haleon's trade names for paracetamol or acetaminophen. According to Haleon, Panadol is marketed in 85 countries, including Australia,[10] Bahrain, Barbados, Belgium,[11] Brazil,[11] Bulgaria,[11] Chile,[11] Egypt, Finland,[11] France,[11] Greece,[11] Honduras, Hong Kong,[11] Indonesia,[11] Ireland,[11] Italy,[11] Kenya,[11] Korea,[11] Lebanon, Malaysia, Netherlands,[11] New Zealand, Nigeria,[12] the Philippines,[11] Peru,[11] Puerto Rico, Pakistan, Qatar, Romania, Saudi Arabia, Singapore, South Africa,[11] Sri Lanka, Switzerland,[11] Taiwan,[11] Thailand, Trinidad and Tobago, Turkey, the United Arab Emirates,[11] the United Kingdom, Vietnam, Malta, Uruguay, North Korea[11] and Oman.

History

After it was first introduced only in clinics in 1953, Panadol started its commercial business in 1955 by Phillips, Scott & Turner, which was acquired by Frederick Stearns & Co, a subsidiary of Sterling Drug Inc. It was advertised as being "gentle on the stomach", since other analgesic agents at the time contained aspirin, a known stomach irritant. In 1955, Panadol was introduced to hospitals in the United Kingdom.[13] Panadol was originally available only by prescription in the UK, but is now available over the counter. In 1983, Sterling introduced Panadol to the United States market.[14] In 1988 Sterling Winthrop was acquired by Eastman Kodak which sold the worldwide over the counter drug business to SmithKline Beecham in 1994.[15] Two weeks later, SmithKline Beecham sold the over-the-counter medication business in the United States, Canada and Puerto Rico to Bayer for US$1 billion.[16] However, North American rights to Panadol were retained by SmithKline.[16] It has been called "one of the most-frequently counterfeited medicines in the world."[17]

Other formulations and packaging

Panadol is sold in different formulations and packaging with different names.[18]

Panadol Extra, an S2 pharmacy-only medicine in Australia, combines 65 mg of caffeine with 500 mg of paracetamol per tablet. Caffeine may improve the analgesic effect of paracetamol. Studies have reached conflicting conclusions regarding the clinical significance of this incremental pain relief.[19] [20]

Panadol Osteo and Panadol Extend Tablets are modified-release formulations of paracetamol.[21] Panadol Osteo is marketed in Australia and New Zealand; its immediate to sustained release ratio is 33% to 66%.[22]

Panadol Rapid Handipak is Panadol Rapid packaged in a slim container of ten 500 mg caplets, designed to appeal to Australian women who are 20 to 35 years of age.[23] [24]

Panadol Cold and Catarrh contains three active ingredients: paracetamol, phenylephrine hydrochloride as a nasal decongestant, and chlorpheniramine maleate to prevent certain allergies.[25]

Panadol Cold and Flu and Panadol Fever and Congestion both combine paracetamol with phenylephrine hydrochloride as a nasal decongestant.[26] [27]

Other brand names

Common brand names include:[28] ! Brand name! Countries
AcamolKenya, Chile, Israel
AceBangladesh, Kenya
AcetPhilippines, Canada, Singapore
AcetalginSwitzerland
AdolKenya, Egypt, Kuwait, Lebanon, Tunisia, Oman
Aeknil[29] India, Philippines
AlvedonSweden, Philippines
ApiretalParaguay, Spain
AtamelVenezuela
AtasolCanada
BiogesicHong Kong, Singapore, Indonesia, Philippines, Myanmar
BuscapinaArgentina, Paraguay, Costa Rica, Guatemala, Honduras, Nicaragua, Panama, El Salvador, Uruguay, Peru, Mexico
CaffetinBosnia & Herzegovina, Croatia, Georgia, Serbia, Russian Federation, Slovenia, Romania, Bulgaria, North Macedonia
CalonalJapan[30]
CalpolCyprus, Malta, India, Kuwait, Philippines, Singapore, Turkey, South Africa, Pakistan, Ireland, Lithuania, Poland, Oman
CemolThailand, Philippines
CentamolBangladesh
CetamolTunisia, Thailand, Egypt, Oman
ColdexTunisia, Israel, Egypt
ColdrexNorth Macedonia, Serbia, Croatia, Romania, Lithuania, Hungary, Poland, Georgia, Slovakia, Czech Republic, Estonia, Bosnia & Herzegovina, Pakistan, Bulgaria, New Zealand, China
Co-TipolMalta
CotibinChile
CrocinIndia
DafalganBelgium, Egypt, Portugal, France, Kuwait, Lebanon, Switzerland, Luxembourg
DaleronBosnia & Herzegovina, Croatia, Lithuania, Latvia, North Macedonia, Romania, Slovenia, Bulgaria, Malta
DeponCyprus, Greece
DexamolIsrael
DolexColombia, Uruguay, Pakistan
DolipraneIndia, France, Lebanon, Tunisia
DoloIndia
EfferalganItaly, Estonia, Egypt, Spain, Croatia, Lithuania, Poland, Portugal, Romania, Tunisia, France, Georgia, Lebanon, North Macedonia, Serbia, Pakistan, Bulgaria, Latvia, Kuwait
EnelfaOman, Germany, Malta, Luxembourg
EuropainHong Kong
Ireland, Kuwait, Netherlands, Portugal, Turkey, Greece, Oman, Georgia, Israel, Canada, United States, Peru, France
FebrectalSpain
FebricetBosnia & Herzegovina, North Macedonia, Serbia
FebridolAustralia
FenmolPakistan
FepIndia
FepamolIndia
FervexEstonia, Lithuania, Tunisia, Bulgaria, Georgia, North Macedonia, Serbia, France, Romania
FevadolPakistan, Kuwait, Oman
GelocatilSpain
GripinTurkey, Paraguay
GelonidaGermany
GesicBangladesh
GripexPoland, Lithuania, Bulgaria, Tunisia
GrippostadBosnia & Herzegovina, Estonia, Croatia, Lithuania, Latvia, Romania, Bulgaria, Russian Federation, Czech Republic, Hungary, Egypt, Serbia, Slovakia, Austria, Spain
HecamolTaiwan
HedexIreland, United Kingdom, Bangladesh
HepaBangladesh
HipaBangladesh
IlvicoSpain, Portugal
InflubeneAustria, Bulgaria, Romania
IpramolPakistan
KafaSwitzerland
KitadolChile, Uruguay, Peru, Paraguay
KodoneGuatemala
LekadolBosnia & Herzegovina, North Macedonia, Croatia, Romania, Bulgaria,
LupocetBosnia & Herzegovina, Croatia
MigraleveIsrael, Portugal, Ireland, Malta, United Kingdom
MexalenAustria, Hungary
MinamolTurkey
MinosetTurkey
NalsaracVietnam
NapaBangladesh, Singapore, Pakistan
NapadolBangladesh
NikoldGeorgia
NeopapUnited States
Neo-PercodanMexico
PamolNew Zealand, Indonesia, Finland, Lithuania, Denmark, Sweden, Estonia
PanadoSouth Africa
PanadolChile, Cyprus, Ecuador, Estonia, Egypt, Finland, Hong Kong, Ireland, Israel, Italy, Kuwait, Lebanon, Lithuania, Latvia, North Macedonia, Myanmar, Malaysia, Netherlands, Philippines, Poland, Portugal, Romania, Singapore, Thailand, Turkey, Taiwan, Greece, Australia, Belgium, Spain, Croatia, New Zealand, Serbia, France, Malta, Peru, Slovakia, Georgia, Indonesia, Tunisia, China, Bosnia & Herzegovina, Luxembourg, Hungary, Oman, Switzerland, United Kingdom, Bulgaria, Bangladesh, Czech Republic
PanamaxTaiwan, Australia
PandaOman, Jordan[31]
PanodilDenmark, Iceland, Norway, Sweden
PanoxenRussian Federation
PanrelivPhilippines
ParacetIceland, Israel, Norway, Bosnia & Herzegovina, Turkey
ParalenCzech Republic, Poland, Slovakia, Croatia, Lithuania, Bosnia & Herzegovina, Bulgaria, North Macedonia, Serbia, Norway
ParamaxNorway, Slovakia, Philippines, Ireland, United Kingdom, Czech Republic, Poland, Hungary, Estonia, Latvia
ParamedTunisia
ParatabsIceland
ParamolIsrael, Romania, Thailand, Egypt, Kuwait, Taiwan, United Kingdom, Paraguay
ParolTurkey, Georgia
PerdolanBelgium, Luxembourg
PerfalganTurkey, Germany, Estonia, Spain, France, Ireland, India, Italy, Lithuania, New Zealand, Oman, Romania, Tunisia, South Africa, United Kingdom, Egypt, Malta, Austria, Israel, Switzerland
PerocetUnited States
PinexDenmark, Iceland, Norway, Sweden, Netherlands
PlicetCroatia, North Macedonia
PyrenolBangladesh
PyrigesicIndia
RevaninKuwait, Oman
RubophenHungary
SanipirinaItaly
SanmolIndonesia
Santa ColdGeorgia
SaridonBulgaria, Brazil, China, Czech Republic, Hungary, Indonesia, Italy, Lithuania, Latvia, Netherlands, Romania, Spain, Kuwait, Oman, Philippines, Portugal
TachipirinVenezuela
TachipirinaItaly
TafirolArgentina, Mexico, Paraguay
TapsinChile, Peru
TermalginSpain
TempraKuwait, Mexico, Venezuela, Egypt, Ecuador, Lebanon, Philippines, Indonesia, Canada
ThomapyrinCroatia, Turkey, Austria, Germany
TipolMalta
TriaminicItaly
TylenolThailand, Lebanon, Brazil, Egypt, Kuwait, Mexico, Oman, Myanmar, Philippines, United States, Uruguay, Venezuela, Netherlands, Canada, China, Lithuania, Paraguay, Switzerland, South Africa
UltracetHong Kong, Malaysia, Singapore, Thailand, Taiwan, Venezuela, South Africa, United States, Brazil, Myanmar, Indonesia, China
UphamolMalaysia
ValadolUnited States
VermidonTurkey
XumadolSpain, Portugal, Chile, Peru
ZolbenSwitzerland, Uruguay, Chile

Notes and References

  1. Web site: Euromonitor International . Acetaminophen benefits from concerns surrounding safety of analgesics . Market Research World . July 26, 2014.
  2. Web site: Paracetamol international brands. Drugs.com. 4 March 2017.
  3. News: A breakdown of the over-the-counter medicines market in Britain in 2016. 29 May 2017. Pharmaceutical Journal. 28 April 2017. 8 September 2017. https://web.archive.org/web/20170908213934/http://www.pharmaceutical-journal.com/20202662.article?amp%3Butm_medium=email&. dead.
  4. http://www.bbc.co.uk/radio4/science/casenotes_tr_20080902.shtml Programme no. 6 – Poisons
  5. Web site: Name of Recipient F11 to next . 2010-01-26.
  6. Web site: Company History . Eurovent . 26 March 2021.
  7. News: Kleeman . Jenny . Why parents are addicted to Calpol . 26 March 2021 . Guardian . 4 June 2019.
  8. Web site: A history of Johnson & Johnson . Johnson & Johnson . 26 February 2021 . 26 March 2021.
  9. News: Nott . George . Personal care: over the counter: Less illness knocks cold & flu lines . 26 March 2021 . The Grocer . 20 December 2020.
  10. News: Pain reliever acetaminophen linked to ADHD . 26 February 2014 . News.com.au . News Limited . Agence France-Presse . Agence France-Presse .
  11. Book: Weiner. Carl P. . Buhimschi. Catalin . Drugs for Pregnant and Lactating Women. 2009. Elsevier Health Sciences. 978-1-4377-2136-2. 37.
  12. News: A peek into sex passing-off cases in Nigeria . NLIPW Trademark Law . 1 . 12 . Ufuoma . Akpotaire . Nigerian Law Intellectual Property Watch . 22 September 2013 . 25 March 2014 .
  13. Web site: GlaxoSmithKline Panadol 50 Years . 2015-05-30 . 2013-06-22 . https://web.archive.org/web/20130622191902/http://gsk.com.my/docs/Panadol%20Booklet.pdf . dead .
  14. Web site: Sterling to Try Again with a Nonaspirin Drug . New York Times . 14 March 1983 . 20 May 2015 . Hollie, Pamela G..
  15. http://www.secinfo.com/dUGc.bs.htm SEC Info| Eastman Kodak Co | 8-K | For 6/30/94
  16. News: Olmos. David R.. German Firm to Reclaim Bayer Aspirin Name : Drugs: It will acquire Sterling Winthrop's over-the-counter business and recover the rights it lost after WWI.. 25 May 2017. Los Angeles Times. 13 Sep 1994.
  17. Web site: Simple counterfeit drugs test developed . UPI . 26 August 2012 . 20 May 2015.
  18. News: GSK launches paracetamol brand in Phl . 30 January 2014 . Sheila . Crisostomo . The Philippine Star .
  19. Derry . Christopher J . Derry . Sheena . Moore . R Andrew . Caffeine as an analgesic adjuvant for acute pain in adults . Cochrane Database of Systematic Reviews . 11 December 2014 . 25502052 . 10.1002/14651858.CD009281.pub3 . 12 . 12 . CD009281. 6485702 .
  20. Web site: Paracetamol with caffeine (Panadol Extra) available over the counter from pharmacies. NPS Radar. National Prescribing Service. 10 August 2012.
  21. Graudins. A.. Chiew. A.. Chan. B.. Overdose with modified-release paracetamol results in delayed and prolonged absorption of paracetamol. Internal Medicine Journal. 40. 1. 2010. 72–76. 1444-0903. 10.1111/j.1445-5994.2009.02096.x. 20561368. 205503437 . PDF.
  22. Andis . Graudins. Hanh Ngoc . Pham. Chris. Salonikas. Daya . Naidoo. Betty . Chan . Early presentation following overdose of modified-release paracetamol (Panadol Osteo) with biphasic and prolonged paracetamol absorption. New Zealand Medical Journal . 1175-8716. 122. 1300. 2009. 64–71. 19701261.
  23. News: GSK's Handipak for Panadol Offers Discreet Portability . Pharmaceutical & Medical Packaging News . 25 March 2014 . 9 December 2007 . David . Vaczek .
  24. Web site: PR positions Panadol Rapid Handipak as the must have accessory for every girl's handbag! . Golden Target Awards . UTS Library, University of Technology, Sydney . 25 March 2014 . 23 November 2013 . https://web.archive.org/web/20131123130254/http://www.lib.uts.edu.au/gta/14237/pr-positions-panadol-rapid-handipak-must-have-accessory-every-girls-handbag . dead .
  25. News: The Nation . 25 December 2008 . GlaxoSmithKline unveils Panadol Cold & Catarrh . Chuks Udo . Okonta . Toba . Agboola .
  26. News: Flu remedies pose dosage risk . Nicole . Mathewson . 20 March 2014 . The Press . Fairfax Media Digital . 25 March 2014 .
  27. Web site: Package leaflet: information for the user – Panadol Cold and Flu 500 mg / 30 mg Film Coated Tablets . GlaxoSmithKline . 25 March 2014 .
  28. Web site: Paracetamol Uses, Dosage, Side Effects, Warnings . dead . https://web.archive.org/web/20201225081427/https://www.drugs.com/international/paracetamol.html . 2020-12-25 . Drugs.com . en.
  29. Web site: Official Site – AEKNIL™ (Paracetamol). Aeknil.com. 6 October 2014.
  30. News: Japan hit with acetaminophen shortage as demand soars amid COVID surge . Mainichi Daily News . 12 November 2023 . en . 10 August 2022.
  31. Web site: Panda - Acetaminophen . Joswe.com . 2015-05-19 . 2012-04-26 . https://web.archive.org/web/20120426041540/http://www.joswe.com/Public/SearchForProduct.aspx?s=Panda . dead .