Para-Chlorophenylpiperazine Explained

para-Chlorophenylpiperazine (pCPP) is a psychoactive drug of the phenylpiperazine class.[1] It is relatively obscure, with limited human use, and produces slightly psychedelic effects. It has been encountered in illicit capsules as a recreational drug similarly to other piperazines like mCPP.[2] Scientific research has demonstrated pCPP to have serotonergic effects, likely acting as a non-selective serotonin receptor agonist and/or releasing agent.[3] [4]

A known use has been in the synthesis of L-745,870.

See also

Notes and References

  1. Web site: www.emcdda.europa.eu .
  2. Web site: www.emcdda.europa.eu .
  3. Fuller RW, Snoddy HD . Comparative effects of p-chloroamphetamine and 1-(p-chlorophenyl)piperazine on 5-hydroxyindole concentration in rat brain . Research Communications in Chemical Pathology and Pharmacology . 29 . 1 . 201–4 . July 1980 . 6157183 .
  4. Maj J, Lewandowska A . Central serotoninmimetic action of phenylpiperazines . Polish Journal of Pharmacology and Pharmacy . 32 . 4 . 495–504 . 1980 . 7255267 .

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