Papuloerythroderma of Ofuji explained

Papuloerythroderma of Ofuji is a rare disorder most commonly found in Japan, characterized by pruritic papules that spare the skinfolds, producing bands of uninvolved cutis, creating the so-called deck-chair sign. Frequently there is associated blood eosinophilia. Skin biopsies reveal a dense lymphohistiocytic infiltrate, eosinophils in the papillary dermis, and increased Langerhans cells (S-100 positive). Systemic steroids are the treatment of choice and may result in long-term remissions.^{[1] [2]}

It was characterized in 1984.^{[3] [4]}

Use of PUVA in treatment has been described.^[5]

See also

• Pruritus
• List of cutaneous conditions
• Erythroderma

Notes and References

1. Book: James WD, Berger TG, Elston DM . 2005 . Andrews' Diseases of the Skin: Clinical Dermatology . 10th . Saunders . 978-0-7216-2921-6 . 56.
2. Book: Rapini RP, Bolognia JL, Jorizzo JL . Dermatology: 2-Volume Set . Mosby . St. Louis . 2007 . 978-1-4160-2999-1 .
3. Torchia D, Miteva M, Hu S, Cohen C, Romanelli P . Papuloerythroderma 2009: two new cases and systematic review of the worldwide literature 25 years after its identification by Ofuji et al . Dermatology . 220 . 4 . 311–320 . March 2010 . 20339287 . 10.1159/000301915 . 23915213 .
4. Ofuji S, Furukawa F, Miyachi Y, Ohno S . Papuloerythroderma . Dermatologica . 169 . 3 . 125–130 . 1984 . 6148269 . 10.1159/000249586 .
5. Book: Burg G, Kempf W . Cutaneous Lymphomas. 30 May 2010. 2005. Informa Health Care. 978-0-8247-2997-4. 365–.