Papuamide Explained

Papuamides A and B are depsipeptides which appear to protect T cells from HIV.[1] They were isolated from the sponge Theonella, and are part of a larger group of structurally similar depsipeptides—also isolated from sponges—including neamphamide A, callipeltin A, and mirabamides A-D.[2]

References

  1. Ford . PW . Gustafson . KR . McKee . TC . Shigematsu . N . Maurizi . LK . Pannell . LK . Williams . DE . de Silva . ED . Lassota . P . Allen . TM . Van Soest . R . Andersen . RJ . Boyd . MR . Papuamides A-D, HIV-Inhibitory and Cytotoxic Depsipeptides from the Sponges Theonella mirabilis and Theonella swinhoei Collected in Papua New Guinea. J. Am. Chem. Soc. . 1999 . 121 . 5899–5909.
  2. Andjelic . CD . Planelles . V . Barrows . LR . Characterizing the Anti-HIV Activity of Papuamide A. Mar Drugs . Marine Drugs . 2008 . 6 . 4 . 528–49 . 2630844 . 19172193 . 10.3390/md20080027 . free .

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