| Papi Khomane | |
| Full Name: | Papi Isaac Khomane[1] |
| Birth Date: | 31 January 1975 |
| Birth Place: | South Africa |
| Height: | 1.80 m |
| Position: | Defender |
| Years1: | 1994–1998 |
| Clubs1: | Jomo Cosmos |
| Caps1: | 91 |
| Goals1: | 0 |
| Years2: | 1998–2007 |
| Clubs2: | Orlando Pirates |
| Caps2: | 151 |
| Goals2: | 0 |
| Totalcaps: | 242 |
| Totalgoals: | 0 |
| Nationalyears1: | 1998–2000 |
| Nationalteam1: | South Africa |
| Nationalcaps1: | 9 |
| Nationalgoals1: | 0 |
Papi Khomane (31 January 1975 – 25 November 2023) was a South African professional footballer who played as a defender. Khomane played club football for Jomo Cosmos and Orlando Pirates; he also earned nine caps for the South Africa national team between 1998 and 2000, featuring at AFCON 2000. He was killed in a car crash while travelling to Newcastle, KwaZulu-Natal, on 25 November 2023, at the age of 48. The crash also killed his mother and brother-in-law.[2]