| Official Name: | Pantufo |
| Settlement Type: | Town |
| Pushpin Map: | Sao Tome |
| Pushpin Label Position: | bottom |
| Pushpin Map Caption: | Location on São Tomé Island |
| Subdivision Type: | Country |
| Subdivision Name: | São Tomé and Príncipe |
| Subdivision Type1: | Island |
| Subdivision Name1: | São Tomé |
| Subdivision Type2: | District |
| Subdivision Name2: | Água Grande |
| Population As Of: | 2012 |
| Population Total: | 1836 |
| Timezone1: | WAT |
| Utc Offset1: | +1 |
| Coordinates: | 0.3144°N 6.7439°W |
Pantufo is a town in the Água Grande District of São Tomé and Príncipe. It is located on the coast, 3 km southeast from the capital São Tomé. Its population is 1,836 (2012 census).[1] It is considered the only urban settlement in the country, apart from the capital.[2]