| Panikos Spyrou | |
| Fullname: | Panayiotis Spyrou |
| Height: | 1.830NaN0 |
| Birth Date: | 17 October 1976 |
| Birth Place: | Nicosia, Cyprus |
| Position: | Defender |
| Years1: | 1997–2000 |
| Years2: | 1998–1999 |
| Clubs2: | → Anorthosis Famagusta (on loan) |
| Years3: | 1999–2000 |
| Years4: | 2000–2002 |
| Clubs4: | Alki Larnaca |
| Years5: | 2003-2004 |
| Clubs5: | → Apollon Limassol (on loan) |
| Years6: | 2002–2005 |
| Years7: | 2005–2011 |
| Clubs7: | Enosis Neon Paralimni |
| Years8: | 2012 |
| Clubs8: | Anagennisi Dherynia |
| Caps1: | 29 |
| Goals1: | 2 |
| Caps2: | 14 |
| Goals2: | 0 |
| Caps3: | 22 |
| Goals3: | 0 |
| Caps4: | 20 |
| Goals4: | 2 |
| Caps5: | 12 |
| Goals5: | 0 |
| Caps6: | 53 |
| Goals6: | 3 |
| Caps7: | 138 |
| Goals7: | 5 |
| Caps8: | 11 |
| Goals8: | 0 |
| Totalcaps: | 299 |
| Totalgoals: | 12 |
| Nationalyears1: | 2002–2003 |
| Nationalteam1: | Cyprus |
| Nationalcaps1: | 11 |
| Nationalgoals1: | 0 |
| Pcupdate: | January 2012 |
| Ntupdate: | July 2009 |
Panayiotis Spyrou born October 17, 1976, in Nicosia, Cyprus is a Cypriot football defender who last played for Anagennisi Dherynia. His former teams are Alki Larnaca, Olympiakos Nicosia, APOEL and Enosis Neon Paralimni where he spent most of his playing years.