| Noc: | PAN |
| Nocname: | Comité Olímpico de Panamá |
| Year: | 2007 |
| Date: | 13–29 July 2007 |
| Games: | Pan American Games |
| Location: | Rio de Janeiro |
| Competitors: | 70 |
| Sports: | 12 |
| Flagbearer: | Irving Saladino |
| Gold: | 1 |
| Silver: | 1 |
| Bronze: | 0 |
| Rank: | 17 |
| Appearances: | auto |
The 15th Pan American Games were held in Rio de Janeiro, Brazil from 13 July 2007 to 29 July 2007. Panama competed with a total number of 70 (48 men and 22 women) athletes in 12 sports.