Pamela Russell Explained

Pamela J. Russell (died February 2022)[1] was an Australian academic researcher of immunology, bladder and prostate research.[2] Russell was awarded Membership of the Order of Australia (AM) for her research on prostate and bladder cancer in 2003.[3]

Biography

Russell was Emeritus Professor at the Institute of Health and Biomedical Innovation, Queensland University of Technology, based at the Translational Research Institute (Australia)[4] and adjunct professor, Centre for Advanced Imaging, University of Queensland.[5]

Education and training

Russell trained in immunology at Walter & Eliza Hall Institute, where she obtained an MSc with Sir Macfarlane Burnet. Subsequently, Russell completed a PhD with Sir Gustav Nossal, on studies of autoimmune diseases.[6] [7]

Russell's postdoctoral training was at the John Curtin School of Medical Research, Canberra, and then she moved to Sydney to take up a postdoctoral position at The Kolling Institute of Medical Research.

Russell joined the APCRC – Q in 2009.[8]

Research

Russell's early work in Immunology on Systemic Lupus Erythematosus (SLE) showed that the immunosuppressive drug, cyclophosphamide, could be successfully used to treat animals with this disease, leading to its use in patients with SLE. Early work WEHI showed that T cells could kill cancer cells.[9] Further studies of autoimmunity were performed by Russell's group at the Kolling Institute specifically SLE.[10] but also some related work in rheumatoid arthritis and in ankylosing spondylitis and its association with HLA-B27.[11] [12]

Russell's focus of the work at the Kolling Institute was on autoimmunity, specifically Systemic Lupus Erythematosus (SLE),[13] but also some related work in rheumatoid arthritis and in ankylosing spondylitis and its association with HLAB27.[14] [15]

In 1984, Russell changed her research focus to cancer and, with Dr. Derek Raghavan, established the Urological Cancer Research Centre at Royal Prince Alfred Hospital/University of Sydney. Russell then directed the Oncology Research Centre (ORC), Prince of Wales Hospital from 1992 to 2010, as conjoint Professor of Medicine, University of New South Wales (UNSW).

Russell then moved to the Translational Research Institute and the Australian Prostate Cancer Research Centre in Queensland in 2012.[16] [17]

Awards

Selected Publications

External links

Notes and References

  1. Web site: 2022-03-03 . In Memory of Emeritus Professor Pamela Russell AM . 2024-07-20 . Prostate Cancer Foundation of Australia . en.
  2. Web site: Pamela Russell. www.qut.edu.au. 12 February 2019.
  3. Web site: 2003 Australia Day Honours List: AC, AO, AM. www.theage.com.au. 12 February 2019. 26 January 2003.
  4. Web site: Pamela Russell. www.tri.edu.au. 12 February 2019.
  5. Web site: Pamela Russell — Australian Prostate Cancer Research Centre - Queensland. www.australianprostatecentre.org. 6 March 2018. live. https://web.archive.org/web/20170801125814/http://www.australianprostatecentre.org/about-us/our-people/pamela-russell. 1 August 2017. dmy-all.
  6. Web site: Pamela Russell — Australian Prostate Cancer Research Centre - Queensland . 2024-07-24 . www.australianprostatecentre.org . en.
  7. Web site: Pamela Russell Translational Research Institute . 2024-07-24 . www.tri.edu.au.
  8. Web site: Professor Pamela Russell — Prostate Cancer Collaborative Research Alliance. www.aus-canprostatealliance.org. en.
  9. Failure Of klebsiella pneumoniae antibodies to cross-react with peripheral blood mononuclear cells from patients with ankylosing spondylitis. Arthritis & Rheumatism. 30. 3. 300–305. 10.1002/art.1780300309. 3551965. 1987. Cameron. Fiona H.. Russell. Pamela J.. Easter. Joan F.. Wakefield. Denis. March. Lyn.
  10. Is a Klebsiella plasmid involved in the aetiology of ankylosing spondylitis in HLA-b27-positive individuals?. Molecular Immunology. 20. 5. 563–566. 10.1016/0161-5890(83)90095-0. 6348514. 1983. Cameron. F.. Russell. P.. Sullivan. J.. Geczy. A..
  11. Web site: Cell Surface Prostate Cancer Antigen for Diagnosis. 22 May 2019.
  12. Web site: Minomic secures key patent in the United States and China. 22 May 2019. 5 September 2018.
  13. Russell, Pamela J., and Alfred D. Steinberg. "Studies of peritoneal macrophage function in mice with systemic lupus erythematosus: Depressed phagocytosis of opsonized sheep erythrocytes in vitro." Clinical immunology and immunopathology 27, no. 3 (1983): 387-402.
  14. Cameron, Fiona H., Pamela J. Russell, Joan F. Easter, Denis Wakefield, and Lyn March. "Failure Of klebsiella pneumoniae antibodies to cross‐react with peripheral blood mononuclear cells from patients with ankylosing spondylitis." Arthritis & Rheumatism 30, no. 3 (1987): 300-305.
  15. Cameron, Fiona H., Pamela J. Russell, John Sullivan, and Andrew F. Geczy. "Is a Klebsiella plasmid involved in the aetiology of ankylosing spondylitis in HLA-B27-positive individuals?." Molecular Immunology 20, no. 5 (1983): 563-566.
  16. Web site: 2022-03-10 . Vale Emeritus Professor Pamela Russell AM FAHMS . 2022-03-12 . Australian Academy of Health and Medical Sciences . en-AU.
  17. Web site: 2022-03-02 . Remembering The Late Professor Pamela Russell AM . 2022-03-12 . Funding Cancer Research Cure Cancer . en-AU.
  18. News: APCRC - Q Researcher Wins PCFA Award. 12 February 2019.
  19. Web site: Fellowship of the Australian Academy of Health and Medical Sciences October 2015. 12 February 2019.
  20. Web site: Pam Russell AM Alumni Excellence Award Health Winner. 12 February 2019.
  21. Singh . Preetiner Pal . Joshi . Swapna . Russell . Pamela J. . Verma . Nirupama D. . Wang . Xiaochun . Khatri . Aparajita . 2011-06-15 . Molecular chemotherapy and chemotherapy: a new front against late-stage hormone-refractory prostate cancer . Clinical Cancer Research. 17 . 12 . 4006–4018 . 10.1158/1078-0432.CCR-11-0248 . 1557-3265 . 21531822.
  22. Hung . Tzong-Tyng . Chan . Jeffrey . Russell . Pamela J. . Power . Carl A. . 2011 . Zoledronic acid preserves bone structure and increases survival but does not limit tumour incidence in a prostate cancer bone metastasis model . PLOS ONE . 6 . 5 . e19389 . 10.1371/journal.pone.0019389 . free . 1932-6203 . 3095598 . 21603655. 2011PLoSO...619389H .
  23. Tang . Catherine . Russell . Pamela J. . Martiniello-Wilks . Rosetta . Rasko . John E. J. . Khatri . Aparajita . September 2010 . Concise review: Nanoparticles and cellular carriers-allies in cancer imaging and cellular gene therapy? . Stem Cells . 28 . 9 . 1686–1702 . 10.1002/stem.473 . 1549-4918 . 2996089 . 20629172.
  24. Khatri . Aparajita . Husaini . Yasmin . Ow . Kim . Chapman . Jane . Russell . Pamela J. . 2009-04-01 . Cytosine deaminase-uracil phosphoribosyltransferase and interleukin (IL)-12 and IL-18: a multimodal anticancer interface marked by specific modulation in serum cytokines . Clinical Cancer Research. 15 . 7 . 2323–2334 . 10.1158/1078-0432.CCR-08-2039 . 1078-0432 . 19318483.
  25. Li . Yong . Song . Emma . Abbas Rizvi . Syed M. . Power . Carl A. . Beretov . Julia . Raja . Chand . Cozzi . Paul J. . Morgenstern . Alfred . Apostolidis . Christos . Allen . Barry J. . Russell . Pamela J. . 2009-02-01 . Inhibition of micrometastatic prostate cancer cell spread in animal models by 213Bilabeled multiple targeted alpha radioimmunoconjugates . Clinical Cancer Research. 15 . 3 . 865–875 . 10.1158/1078-0432.CCR-08-1203 . 1078-0432 . 19188157.

This article is licensed under the GNU Free Documentation License. It uses material from the Wikipedia article "Pamela Russell".

Except where otherwise indicated, Everything.Explained.Today is © Copyright 2009-2024, A B Cryer, All Rights Reserved. Cookie policy.