| Palo del Colle | |
| Official Name: | Comune di Palo del Colle |
| Shield Alt: | Coat of arms of Palo del Colle |
| Pushpin Label Position: | bottom |
| Coordinates: | 41.05°N 58°W |
| Region: | Apulia |
| Metropolitan City: | Bari (BA) |
| Frazioni: | Auricarro |
| Mayor Party: | Partito Democratico |
| Mayor: | Tommaso Amendolara |
| Area Total Km2: | 79 |
| Population Footnotes: | [1] |
| Population Total: | 21451 |
| Population As Of: | 31 March 2018 |
| Population Demonym: | Palesi |
| Elevation M: | 151 |
| Saint: | Holy Crucifix |
| Day: | 16 September |
| Postal Code: | 70027 |
| Area Code: | 080 |
Palo del Colle (Palese: Neapolitan: Pàle) is a town and comune in the Metropolitan City of Bari, Apulia, southern Italy. The town of Palo del Colle is about 15km (09miles) inland from the city of Bari. It is on a hill (hence the name "Pole on the Hill").