Palmer Creek is a stream in Chariton County in the U.S. state of Missouri. It is a tributary of the Missouri River.
The stream headwaters arise at 39.5317°N -93.0408°W and it flows generally south passing the community of Indian Grove.[1] It continues to the south entering the Missouri River floodplain passing under US Route 24 approximately midway between Brunswick and Keytesville. The stream passes through the Cut-Off Lake and enters the Missouri just west of the Chariton River confluence[2] at 39.3164°N -92.9683°W.
Palmer Creek was named after Maillard Palmer, the first state representative from Chariton County.[3]