Palazzo Serristori is a Renaissance style palace located between Piazza Demidoff and the Lungarno Serristori in Oltrarno, in the neighborhood of San Niccolò of Florence, region of Tuscany, Italy.
The palace was initially constructed in 1520–1522, by the bishop of Bitetto, Lorenzo Serristori. The Serristori family is originally from the small Tuscan town of Figline, and the last name derives from Ser Ristoro, a local magistrate who is commemorated by a statue in this palace's entrance stairwell. The Serristori coat of arms (1515) of the lineage above the portal facing San Niccolò and was modified by Pope Leo X, who added three lilies to the three existing stars.
The original plan of the palace had a classic U shape of clear Roman derivation, with a quadrangular inside courtyard that looked over an important garden through a loggia with three arched windows. Historians suppose, by certain analogies, that the architect was Giuliano da San Gallo, active at that time in Florence.
Lorenzo's nephew Averardo, a diplomat for Cosimo I de' Medici, enlarged the palace and gardens facing the Arno. During the 16th-century, the palace is further enlarged under the patronage of Antonio Serristori, governor of the Livorno port. He enlarged and transformed the "casa dell'orto" in a palace endowed with an elaborately decorated ballroom. This transformation was designed by the architect Gherardo Silvani, who was well-paid according to documents. The architect Felice Gamberai helped complete the ballroom which is flanked bythree large windows surmounted by other smaller windows, and housing Murano glass chandeliers. The vaults and walls are decorated by Pier Paolo Lippi, Agnolo Gori, and Cosimo Ulivelli.
In 1803, the architect Giuseppe Manetti was commissioned by then Senator Averardo Serristori to refurbish the palace. The size of the palace and gardens was reduced in size during the enlargement of the Lungarno along the river. The architect Mariano Falciani created a new river facade. In 1822 housed briefly the Count Demidoff, who then moved to the nearby Palazzo Amici-Demidoff. Julie Clary, the sister-in-law of Napoleon, lived here in exile until her death in 1845.
The palace returned in the 19th century to the property of the Serristori family. The interior has a helical staircase (1650) by Gherardo Silvani.
In March 2020 the building was purchased by the Taiwanese group LDC Hotels & Resorts which at the end of 2021 began an important restoration and renovation work and new residential apartments will be available from 2023[1]