| Palaiokomi | |
| Name Local: | Παλαιοκώμη |
| Type: | community |
| Periph: | Central Macedonia |
| Periphunit: | Serres |
| Municipality: | Amphipolis |
| Population: | 1195 |
| Population As Of: | 2021 |
| Coordinates: | 40.8714°N 23.9017°W |
| Licence: | ΕΡ |
Palaiokomi (Greek, Modern (1453-);: Παλαιοκώμη) is a village in the municipality of Amphipolis in the regional unit of Serres. It is the second largest village of the municipality of Amphipolis in terms of population (1,195 inhabitants in 2021), after Rodolivos.