| Paderna | |
| Official Name: | Comune di Paderna |
| Coordinates: | 44.8167°N 61°W |
| Region: | Piedmont |
| Province: | Alessandria (AL) |
| Mayor: | Matteo Gualco |
| Area Total Km2: | 4.42 |
| Population Footnotes: | [1] |
| Population Total: | 205 |
| Population As Of: | 30 November 0271 |
| Population Demonym: | Padernesi |
| Elevation M: | 300 |
| Postal Code: | 15050 |
| Area Code: | 0131 |
Paderna is a comune (municipality) in the Province of Alessandria in the Italian region Piedmont, located about 100km (100miles) southeast of Turin and about 25km (16miles) southeast of Alessandria.
Paderna borders the following municipalities: Carezzano, Costa Vescovato, Spineto Scrivia, Tortona, and Villaromagnano.