L-serine-phosphatidylethanolamine phosphatidyltransferase explained

L-serine-phosphatidylethanolamine phosphatidyltransferase
Ec Number:	2.7.8.29

L-serine-phosphatidylethanolamine phosphatidyltransferase (phosphatidylserine synthase 2, serine-exchange enzyme II, PTDSS2 (gene)) is an enzyme with systematic name L-1-phosphatidylethanolamine:L-serine phosphatidyltransferase.^{[1] [2]} This enzyme catalyses the following chemical reaction

\rightleftharpoons L-1-phosphatidylserine + ethanolamine

This enzyme catalyses replacement of a polar head group of phosphatidylethanolamine with L-serine.

Notes and References

1. Stone SJ, Vance JE . Cloning and expression of murine liver phosphatidylserine synthase (PSS)-2: differential regulation of phospholipid metabolism by PSS1 and PSS2 . The Biochemical Journal . 342 . 57–64 . August 1999 . 10432300 . 1220436 . 10.1042/0264-6021:3420057 . 1.
2. Tomohiro S, Kawaguti A, Kawabe Y, Kitada S, Kuge O . Purification and characterization of human phosphatidylserine synthases 1 and 2 . The Biochemical Journal . 418 . 2 . 421–9 . March 2009 . 19014349 . 10.1042/bj20081597 .