PTBP2 explained

Polypyrimidine tract binding protein 2, also known as PTBP2, is a protein which in humans is encoded by the PTBP2 gene.^{[1] [2]}

Function

The protein encoded by this gene binds to the intronic cluster of RNA regulatory elements, downstream control sequence (DCS). It is implicated in controlling the assembly of other splicing-regulatory proteins. This protein is very similar to the polypyrimidine tract-binding protein PTBP1 but it is expressed primarily in the brain.^[2]

Notes and References

1. Markovtsov V, Nikolic JM, Goldman JA, Turck CW, Chou MY, Black DL . Cooperative assembly of an hnRNP complex induced by a tissue-specific homolog of polypyrimidine tract binding protein . Mol. Cell. Biol. . 20 . 20 . 7463–79 . October 2000 . 11003644 . 86300 . 10.1128/MCB.20.20.7463-7479.2000.
2. Web site: Entrez Gene: PTBP2 polypyrimidine tract binding protein 2.